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翻修全膝关节置换术病因的趋势变化:17 年回顾研究

Trend Shift in the Cause of Revision Total Knee Arthroplasty over 17 Years.

机构信息

Department of Orthopedic Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.

Department of Orthopedic Surgery, Segyero Hospital, Gwangju, Korea.

出版信息

Clin Orthop Surg. 2023 Apr;15(2):219-226. doi: 10.4055/cios21106. Epub 2022 Jun 30.

Abstract

BACKGROUND

The number of revision total knee arthroplasty (TKA) has been increasing. Although many studies have analyzed the causes of revision TKA in Western countries, a limited number of studies have analyzed changes in causes of or trends in revision TKA in Asia. This study analyzed and determined the frequency and causes of failures after TKA in our hospital. We also analyzed the differences and trends over the past 17 years.

METHODS

A total of 296 revision TKAs performed in a single institution from 2003 to 2019 were analyzed. During the 17-year study period, patients who had undergone primary TKA between 2003 and 2011 were classified into a past group, while those who had undergone primary TKA from 2012 to 2019 were classified into a recent group. A revision performed within 2 years after primary TKA was defined as early revision. Further, differences in causes of revision TKA according to the interval from primary TKA to revision TKA were determined. The causes of revision TKA were analyzed through a comprehensive analysis of patients' medical records.

RESULTS

Overall, infection was the most common cause of failure (151/296 cases, 51.0%). Compared to the past group, the recent group had a relatively higher proportion of patients undergoing revision TKA for mechanical loosening (past group, 19.1% vs. recent group, 31.9%) and instability (11.2% vs. 13.5%) and a relatively lower proportion of patients undergoing revision TKA for infection (56.2% vs. 48.8%), polyethylene (PE) wear (9.0% vs. 2.9%), osteolysis (2.2% vs. 1.9%), and malalignment (2.2% vs. 1.0%). On comparison according to the interval from primary TKA to revision TKA, the rate of infection relatively decreased, whereas the rate of mechanical loosening and instability relatively increased in the late revision TKA compared to the early revision TKA.

CONCLUSIONS

Infection and aseptic loosening were the most common reasons of revision TKA in both past and recent groups. Compared to the past, revision TKA due to PE wear has decreased significantly and revision TKA due to mechanical loosening has relatively increased recently. Orthopedic surgeons need to be aware of recent trends in mechanisms of failure and should try to recognize and address the probable causes in TKA.

摘要

背景

翻修全膝关节置换术(TKA)的数量一直在增加。尽管许多研究已经分析了西方国家翻修 TKA 的原因,但为数不多的研究分析了亚洲翻修 TKA 的原因变化或趋势。本研究分析并确定了我院 TKA 后失败的频率和原因。我们还分析了过去 17 年来的差异和趋势。

方法

分析了 2003 年至 2019 年在一家医疗机构进行的 296 例翻修 TKA。在 17 年的研究期间,将 2003 年至 2011 年期间接受初次 TKA 的患者分为过去组,而将 2012 年至 2019 年期间接受初次 TKA 的患者分为近期组。初次 TKA 后 2 年内进行的翻修定义为早期翻修。此外,根据初次 TKA 至翻修 TKA 的间隔时间,确定了翻修 TKA 的原因差异。通过综合分析患者的病历,对翻修 TKA 的原因进行了分析。

结果

总体而言,感染是失败的最常见原因(151/296 例,51.0%)。与过去组相比,近期组因机械松动(过去组 19.1%,近期组 31.9%)和不稳定(11.2%,近期组 13.5%)而接受翻修 TKA 的患者比例相对较高,而因感染(56.2%,近期组 48.8%)、聚乙烯(PE)磨损(9.0%,近期组 2.9%)、溶骨(2.2%,近期组 1.9%)和对线不良(2.2%,近期组 1.0%)而接受翻修 TKA 的患者比例相对较低。根据初次 TKA 至翻修 TKA 的间隔时间进行比较,与早期翻修相比,晚期翻修感染的比例相对降低,而机械松动和不稳定的比例相对增加。

结论

感染和无菌性松动是过去和近期两组翻修 TKA 的最常见原因。与过去相比,因 PE 磨损而进行的翻修 TKA 显著减少,而因机械松动而进行的翻修 TKA 最近相对增加。骨科医生需要了解失败机制的最新趋势,并尝试在 TKA 中识别和解决可能的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10060782/bd2293b8f642/cios-15-219-g001.jpg

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