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连枷胸损伤手术治疗患者的生活质量和临床结局:一项多中心前瞻性队列研究。

Quality of life and clinical outcomes of operatively treated patients with flail chest injuries: A multicentre prospective cohort study.

作者信息

Hoepelman Ruben J, Minervini Fabrizio, Beeres Frank J P, van Wageningen Bas, IJpma Frank F, van Veelen Nicole M, Lansink Koen W W, Hoogendoorn Jochem M, van Baal Mark C P, Groenwold Rolf H H, Houwert Roderick M

机构信息

Department of Trauma Surgery, University Medical Center Utrecht, Utrecht, Netherlands.

Department of Thoracic Surgery, Luzerner Kantonsspital, Lucerne, Switzerland.

出版信息

Front Surg. 2023 Mar 15;10:1156489. doi: 10.3389/fsurg.2023.1156489. eCollection 2023.

Abstract

INTRODUCTION

Most studies about rib fractures focus on mortality and morbidity. Literature is scarce on long term and quality of life (QoL) outcomes. Therefore, we report QoL and long-term outcomes after rib fixation in flail chest patients.

METHODS

A prospective cohort study of clinical flail chest patients admitted to six level 1 trauma centres in the Netherlands and Switzerland between January 2018 and March 2021. Outcomes included in-hospital outcomes and long-term outcomes, such as QoL measurements 12 months after hospitalization using the EuroQoL five dimensions (EQ-5D) questionnaire.

RESULTS

Sixty-one operatively treated flail chest patients were included. Median hospital length of stay was 15 days and intensive care length of stay was 8 days. Sixteen (26%) patients developed pneumonia and two (3%) died. One year after hospitalization the mean EQ5D score was 0.78. Complication rates were low and included hemothorax (6%) pleural effusion (5%) and two revisions of the implant (3%). Implant related irritation was commonly reported by patients ( = 15, 25%).

CONCLUSIONS

Rib fixation for flail chest injuries can be considered a safe procedure and with low mortality rates. Future studies should focus on quality of life rather than solely short-term outcomes. Registered in the Netherlands Trial Register NTR6833 on 13/11/2017 and the Swiss Ethics Committees Registration Number 2019-00668.

摘要

引言

大多数关于肋骨骨折的研究都集中在死亡率和发病率上。关于长期和生活质量(QoL)结果的文献很少。因此,我们报告了连枷胸患者肋骨固定术后的生活质量和长期结果。

方法

对2018年1月至2021年3月期间在荷兰和瑞士的六个一级创伤中心收治的临床连枷胸患者进行一项前瞻性队列研究。结果包括住院结果和长期结果,例如使用欧洲五维健康量表(EQ-5D)问卷在住院12个月后测量生活质量。

结果

纳入61例接受手术治疗的连枷胸患者。中位住院时间为15天,重症监护住院时间为8天。16例(26%)患者发生肺炎,2例(3%)死亡。住院一年后,EQ5D平均得分为0.78。并发症发生率较低,包括血胸(6%)、胸腔积液(5%)和2例植入物翻修(3%)。患者普遍报告了与植入物相关的刺激(n = 15,25%)。

结论

连枷胸损伤的肋骨固定可被视为一种安全的手术,死亡率较低。未来的研究应关注生活质量,而不仅仅是短期结果。于2017年11月13日在荷兰试验注册中心注册,注册号为NTR6833,并在瑞士伦理委员会注册,注册号为2019-00668。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5918/10050428/ebe3dd62abd0/fsurg-10-1156489-g001.jpg

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