Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China.
Curr Eye Res. 2023 Jul;48(7):651-659. doi: 10.1080/02713683.2023.2192896. Epub 2023 Apr 3.
To evaluate the correlation between lens density measured by IOL-Master 700 based on swept-source optical coherence tomography (SS-OCT) technology and the phacodynamic parameters of Centurion phacoemulsification in cataract surgery.
This prospective study included 66 patients (83 eyes) with age-related cataracts. Using the Lens Opacities Classification System III (LOCS III), the lens nuclear color (NC), lens nuclear opalescence (NO), cortical (C), and posterior subcapsular (P) opacities were obtained. Six meridian orientations of IOL-Master 700 images were captured, and the lens and nuclear regions were analyzed using ImageJ to generate the average lens nucleus density (AND) and average lens density (ALD). Phacodynamic parameters were recorded. The correlation between lens density and the phacodynamic parameters was analyzed. According to the AND, patients were divided into four groups (soft, medium-hard, hard, and extremely hard nucleus), and the phacodynamic parameters were compared among groups.
The correlation between the AND obtained by LOCS III grading and SS-OCT-based cataract quantification system score (NC and NO) was statistically significant ( = 0.795, =0.794, both = .000). AND correlated significantly with cumulative dissipated energy (CDE, = 0.545, = .000), total ultrasound time (TUST, = 0.354, = .001), and total torsional ultrasound time (TTUT, = 0.314, = .004). Among the four groups divided by AND, the difference in CDE ( = 0.002, < 0.001, = 0.002) was statistically significant.
AND measured by IOL-Master 700, SS-OCT correlated significantly with LOCS III classification and phacodynamic parameters of the Centurion system, especially with CDE, TUST, and TTUT. AND can be used as an indicator for quantitative evaluation and help inform the surgical plan.
评估基于扫频源光相干断层扫描（SS-OCT）技术的 IOL-Master 700 测量的晶状体密度与白内障手术中 Centurion 超声乳化的光力学参数之间的相关性。
本前瞻性研究纳入 66 例（83 只眼）年龄相关性白内障患者。采用晶状体混浊分类系统 III（LOCS III），获取晶状体核颜色（NC）、晶状体核混浊（NO）、皮质（C）和后囊下混浊（P）。采集 IOL-Master 700 图像的 6 个子午线方位，使用 ImageJ 分析晶状体和核区，生成平均晶状体核密度（AND）和平均晶状体密度（ALD）。记录光力学参数。分析晶状体密度与光力学参数之间的相关性。根据 AND 将患者分为 4 组（软核、中硬核、硬核和极硬核），比较组间光力学参数。
LOCS III 分级法获得的 AND 与基于 SS-OCT 的白内障定量系统评分（NC 和 NO）之间的相关性具有统计学意义（ = 0.795， =0.794，均 = .000）。AND 与累积消散能量（CDE， = 0.545， = .000）、总超声时间（TUST， = 0.354， = .001）和总扭转超声时间（TTUT， = 0.314， = .004）显著相关。根据 AND 分为 4 组后，CDE 的差异具有统计学意义（ = 0.002， < 0.001， = 0.002）。
IOL-Master 700 测量的 AND 与 LOCS III 分类和 Centurion 系统的光力学参数显著相关，尤其是与 CDE、TUST 和 TTUT 相关。AND 可作为定量评估的指标，有助于制定手术计划。
