Mansoura Nephrology and Dialysis Unit, Department of Internal Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Rheumatology and Immunology Unit, Department of Internal Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Int Urol Nephrol. 2023 Nov;55(11):2905-2914. doi: 10.1007/s11255-023-03556-7. Epub 2023 Apr 2.
The aims of the study are to explore the prevalence and risk factors of anxiety and depression in hemodialysis (HD) patients and to study their relationship with quality of life (QOL).
This cross-sectional study involved 298 HD patients. Sociodemographic, clinical, and laboratory data of the patients were obtained from their records. Anxiety and depression were assessed by utilizing Hospital Anxiety and Depression Scale (HADS). In addition, QOL of the patients were evaluated by fulfilling the Kidney Disease Quality of Life-36.
This study included 298 HD patients (male 59.1%) with a median age of 49 years. Abnormal and borderline cases of anxiety were recognized in 49.6%, 26.2% of the patients, respectively, while depression cases and borderline cases were identified in 55 and 28.2% of the patients, respectively. Percentages of females (41 and 48% vs 26.4%, respectively), and patients who were not working (92.3 and 93.9% vs 72.2%, respectively) increased significantly in borderline and abnormal anxiety groups. Patients who did not work, led an inactive lifestyle, and smoked had considerably greater percentages in the borderline and abnormal HADS-depression categories than normal patients. Abnormal cases of depression and anxiety had significantly longer duration of HD than other two groups. Abnormal and borderline cases of anxiety and depression had worse QOL components than the normal patients.
Anxiety and depression are prevalent among HD patients in Egypt, and several sociodemographic and clinical risk factors are associated. In addition, these mental disorders are associated with poor QOL.
本研究旨在探讨血液透析（HD）患者焦虑和抑郁的患病率和危险因素，并研究其与生活质量（QOL）的关系。
本横断面研究纳入了 298 名 HD 患者。从患者的病历中获取了他们的社会人口学、临床和实验室数据。采用医院焦虑抑郁量表（HADS）评估焦虑和抑郁。此外，通过填写肾脏病生活质量-36 评估患者的 QOL。
本研究纳入了 298 名 HD 患者（男性占 59.1%），中位年龄为 49 岁。分别有 49.6%和 26.2%的患者存在焦虑异常和边缘病例，分别有 55%和 28.2%的患者存在抑郁病例和边缘病例。女性（41%和 48%比 26.4%）和不工作的患者（92.3%和 93.9%比 72.2%）在边缘和异常焦虑组中显著增加。不工作、生活方式不活跃和吸烟的患者在边缘和异常 HADS 抑郁类别中的比例明显高于正常患者。异常和边缘的焦虑和抑郁病例的 HD 持续时间明显更长。异常和边缘的焦虑和抑郁病例的 QOL 各组成部分均较正常患者差。
焦虑和抑郁在埃及 HD 患者中较为常见，存在多种社会人口学和临床危险因素。此外，这些精神障碍与较差的 QOL 相关。
