, San Jose, USA.
Immunol Res. 2023 Oct;71(5):673-677. doi: 10.1007/s12026-023-09377-1. Epub 2023 Apr 3.
Most viral, bacterial, fungal, and protozoan pathogens can cause latent infections. Latent pathogens can be reactivated from any intentional medical treatment causing immune system suppression, pathogen infections, malnutrition, stress, or drug side effects. These reactivations of latent pathogen infections can be dangerous and even lethal, especially in immuno-suppressed individuals. The latent pathogen infections in an individual can be classified and updated on a periodic basis in a four category system by whether or not an individual's immune system is damaged and by whether or not these latent infections will assist other active or latent pathogen infections. Such a classification system for latent infections by viral, bacterial, fungal, and protozoan parasite pathogens would be practical and useful and indicate whether certain medical treatments will be dangerous for transmitting or reactivating an individual's latent pathogen infections. This classification system will immediately provide latent pathogen infection status information that is potentially vital for emergency care and essential for quickly and safely selecting tissue or organ transplant donors and recipients, and it will significantly increase the safety of medical care for both patients and medical care providers.
大多数病毒、细菌、真菌和原生动物病原体都可能导致潜伏感染。潜伏病原体可以通过任何导致免疫系统抑制、病原体感染、营养不良、压力或药物副作用的有意治疗而被重新激活。这些潜伏病原体感染的重新激活可能是危险的，甚至是致命的，尤其是在免疫抑制个体中。个体中的潜伏病原体感染可以通过个体的免疫系统是否受损以及这些潜伏感染是否会协助其他活跃或潜伏的病原体感染，在一个四分类系统中进行分类和定期更新。这种病毒、细菌、真菌和原生动物寄生虫病原体潜伏感染的分类系统将是实用和有用的，并表明某些治疗方法对于传播或重新激活个体的潜伏病原体感染是否危险。该分类系统将立即提供潜在病原体感染状态信息，这对于紧急护理至关重要，对于快速安全地选择组织或器官供体和受者也是必不可少的，并且将显著提高患者和医疗保健提供者的医疗保健安全性。
