Lanzhou University Second Hospital, Lanzhou University, Lanzhou, 730000, China.
Xiangya School of Nursing, Central South University, Changsha, China.
J Tissue Viability. 2023 May;32(2):213-227. doi: 10.1016/j.jtv.2023.03.003. Epub 2023 Mar 30.
The aim of this network meta-analysis is to analyze the difference in therapeutic effects between moist dressings and traditional dressings in the treatment of pressure injury (PI), explore the healing, healing time, direct cost, and number of dressing changes of different moist dressings for the management of pressure injuries.
The incidence of pressure injury is high and the burden of disease is high, but there is no consensus on how to choose moist dressing treatment.
A systematic review with network meta-analysis was performed.
We searched the Chinese Biomedicine Literature Database and China National Knowledge Infrastructure, Wanfang Database, VIP database, PubMed, Web of Science, EMBASE.com, CENTRAL (Cochrane Central Register of Controlled Trials) and CINAHL to obtain randomized controlled trials (RCTs) on the treatment of PI with moist dressings.
R studio software and Stata 16.0 software were used to compare different moist dressings and traditional dressings.
41 RCTs of moist dressings in the treatment of PI were included. A total of seven kinds of moist dressings, Vaseline gauze and traditional gauze dressing were involved. All RCTs were at a medium to high risk of bias. Overall, moist dressings had more advantages than traditional dressings in terms of various outcome indicators.
The effect of moist dressings in treating PI is more advantageous than traditional dressings. However, in terms of direct cost and the number of dressings changes, more research is needed to improve the credibility of the network meta-analysis. The results of the network meta-analysis show that the silver ion dressing and alginate dressing are the best choices in the treatment of PI.
This study is a network meta-analysis, which does not require the participation of patients and the public.
本网状荟萃分析旨在分析湿性敷料与传统敷料治疗压力性损伤(PI)的疗效差异,探讨不同湿性敷料治疗压力性损伤的愈合情况、愈合时间、直接成本和换药次数。
压力性损伤的发病率高,疾病负担重,但对于如何选择湿性敷料治疗尚无共识。
系统评价和网状荟萃分析。
检索中国生物医学文献数据库、中国知网、万方数据库、维普数据库、PubMed、Web of Science、EMBASE.com、Cochrane 中央对照试验注册库(CENTRAL)和 CINAHL,获取湿性敷料治疗 PI 的随机对照试验(RCT)。
使用 R 工作室软件和 Stata 16.0 软件比较不同的湿性敷料和传统敷料。
共纳入 41 项湿性敷料治疗 PI 的 RCT。共涉及 7 种湿性敷料和凡士林纱布与传统纱布敷料。所有 RCT 均存在中至高偏倚风险。总体而言,湿性敷料在各种结局指标上均优于传统敷料。
湿性敷料治疗 PI 的效果优于传统敷料。然而,在直接成本和换药次数方面,需要进一步的研究来提高网络荟萃分析的可信度。网络荟萃分析的结果表明,银离子敷料和藻酸盐敷料是 PI 治疗的最佳选择。
无患者或公众参与。本研究为网络荟萃分析,无需患者和公众参与。