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促进伤口愈合:对丝胶蛋白和潜在敷料乳酸菌的综合综述。

Enhancing Wound Healing: A Comprehensive Review of Sericin and L. as Potential Dressings.

作者信息

Borges Ana, Calvo María Luisa Martín, Vaz Josiana A, Calhelha Ricardo C

机构信息

Centro de Investigação da Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.

Grupo de Investigación en Desarrollo y Evaluación de Formas Farmacéuticas y Sistemas de Liberación Controlada, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno s/n, 37007 Salamanca, Spain.

出版信息

Materials (Basel). 2024 Aug 24;17(17):4199. doi: 10.3390/ma17174199.

DOI:10.3390/ma17174199
PMID:39274589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11395905/
Abstract

Wound healing, a complex physiological process orchestrating intricate cellular and molecular events, seeks to restore tissue integrity. The burgeoning interest in leveraging the therapeutic potential of natural substances for advanced wound dressings is a recent phenomenon. Notably, Sericin, a silk-derived protein, and L. (), a botanical agent, have emerged as compelling candidates, providing a unique combination of natural elements that may revolutionize conventional wound care approaches. Sericin, renowned for its diverse properties, displays unique properties that accelerate the wound healing process. Simultaneously, , with its diverse pharmacological compounds, shows promise in reducing inflammation and promoting tissue regeneration. As the demand for innovative wound care solutions increases, understanding the therapeutic potential of natural products becomes imperative. This review synthesizes current knowledge on Sericin and , envisioning their future roles in advancing wound management strategies. The exploration of these natural substances as constituents of wound dressings provides a promising avenue for developing sustainable, effective, and biocompatible materials that could significantly impact the field of wound healing.

摘要

伤口愈合是一个复杂的生理过程,协调着错综复杂的细胞和分子事件,旨在恢复组织完整性。最近,人们对利用天然物质的治疗潜力开发先进伤口敷料的兴趣日益浓厚。值得注意的是,丝胶蛋白(一种源自丝绸的蛋白质)和[此处原文缺失植物名称](一种植物制剂)已成为引人注目的候选物,它们提供了一种独特的天然元素组合,可能会彻底改变传统的伤口护理方法。丝胶蛋白以其多样的特性而闻名,具有加速伤口愈合过程的独特性质。同时,[此处原文缺失植物名称]因其多种药理化合物,在减轻炎症和促进组织再生方面显示出前景。随着对创新伤口护理解决方案需求的增加,了解天然产物的治疗潜力变得至关重要。本综述综合了关于丝胶蛋白和[此处原文缺失植物名称]的现有知识,展望它们在推进伤口管理策略方面的未来作用。将这些天然物质用作伤口敷料的成分进行探索,为开发可持续、有效且生物相容的材料提供了一条有前景的途径,这可能会对伤口愈合领域产生重大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/52cd63c0f5c5/materials-17-04199-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/b40b5dc12317/materials-17-04199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/eee1954bdaa7/materials-17-04199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/102ff0c931b2/materials-17-04199-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/5db3f3fd6520/materials-17-04199-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/52cd63c0f5c5/materials-17-04199-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/b40b5dc12317/materials-17-04199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/eee1954bdaa7/materials-17-04199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/102ff0c931b2/materials-17-04199-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/5db3f3fd6520/materials-17-04199-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/11395905/52cd63c0f5c5/materials-17-04199-g005.jpg

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Sericin improves memory and sociability impairments evoked by transient global cerebral ischemia through suppression of hippocampal oxidative stress, inflammation, and apoptosis.丝胶通过抑制海马氧化应激、炎症和细胞凋亡改善短暂性全脑缺血诱导的记忆和社交障碍。
Chin J Physiol. 2023 Jul-Aug;66(4):209-219. doi: 10.4103/cjop.CJOP-D-23-00006.
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Polysaccharide based transdermal patches for chronic wound healing: Recent advances and clinical perspective.
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Carbohydr Polym. 2023 Sep 15;316:121038. doi: 10.1016/j.carbpol.2023.121038. Epub 2023 May 30.
4
Recent advances in bacterial cellulose-based antibacterial composites for infected wound therapy.基于细菌纤维素的抗菌复合材料在感染性创面治疗中的最新进展。
Carbohydr Polym. 2023 Sep 15;316:121082. doi: 10.1016/j.carbpol.2023.121082. Epub 2023 Jun 2.
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Recent advances in novel materials and techniques for developing transparent wound dressings.新型材料和技术在透明伤口敷料开发中的最新进展。
J Mater Chem B. 2023 Jul 12;11(27):6201-6224. doi: 10.1039/d3tb00639e.
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