人工关节置换术中的球孢子菌病：文献综述及病例报告
Coccidioidomycosis in Joint Replacement: A Review of the Literature With Case Presentations.
作者信息
Giordani Francesca Anna, Kiernan Brendan, Giordani Mauro, Darrow Morgan, Thorpe Steven, Meehan John P
机构信息
Department of Orthopaedic Surgery, University of California Davis Health, Sacramento, CA, USA.
出版信息
Arthroplast Today. 2023 Mar 28;21:101123. doi: 10.1016/j.artd.2023.101123. eCollection 2023 Jun.
Coccidioidomycosis is a fungal infection endemic to certain regions of the Americas. In some cases, the organism may infect the musculoskeletal system, resulting in a prosthetic joint infection (PJI). Due to its difficulty in diagnosis, treatment of coccidioidomycosis in PJI is often delayed. Furthermore, with limited number of case reports, a standard of care in treatment has yet to be established. We present 2 cases of coccidioidomycosis PJI, the extensive evaluation that led to the diagnosis, and the treatment provided. This report highlights the natural progression of coccidioidomycosis in a prosthetic joint, the diagnostic features including histology, advanced imaging, and final treatment administered.
球孢子菌病是一种在美洲某些地区流行的真菌感染。在某些情况下，该病原体可能感染肌肉骨骼系统，导致人工关节感染（PJI）。由于其诊断困难，PJI中球孢子菌病的治疗往往会延迟。此外，由于病例报告数量有限，尚未确立治疗的标准护理方案。我们报告2例球孢子菌病PJI病例，导致诊断的广泛评估以及所提供的治疗。本报告强调了球孢子菌病在人工关节中的自然病程、包括组织学、先进影像学在内的诊断特征以及最终给予的治疗。
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