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颅内出血导致的Brugada综合征拟表型

Brugada Phenocopy Caused by Intracranial Hemorrhage.

作者信息

Branco Tiago, Barbosa Ana, Cunha Nelson, Gouveia João, Lopes João M

机构信息

Serviço de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, PRT.

Departament de Cardiologia, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Centro Cardiovascular da Universidade de Lisboa, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Lisboa, PRT.

出版信息

Cureus. 2023 Mar 2;15(3):e35687. doi: 10.7759/cureus.35687. eCollection 2023 Mar.

DOI:10.7759/cureus.35687
PMID:37012940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10066709/
Abstract

Brugada syndrome (BrS) is a congenital channelopathy associated with an increased risk of malignant ventricular arrhythmias and sudden cardiac death in individuals without any structural cardiopathy. Brugada phenocopies (BrPs) are clinical entities that present electrocardiographic patterns similar to those of BrS that are elicited only under transitory pathophysiological conditions, with normalization of the ECG pattern after the resolution of those conditions. We present a rare case of BrP due to intracranial hemorrhage. We also present and discuss the diagnostic criteria for BrPs and their application to this case.

摘要

Brugada综合征（BrS）是一种先天性离子通道病，在无任何结构性心脏病的个体中，其发生恶性室性心律失常和心源性猝死的风险增加。Brugada综合征拟表型（BrP）是指临床病症呈现出与BrS相似的心电图模式，且仅在短暂的病理生理条件下诱发，这些条件解除后心电图模式恢复正常。我们报告了一例因颅内出血导致的罕见BrP病例。我们还介绍并讨论了BrP的诊断标准及其在该病例中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/0698488549cd/cureus-0015-00000035687-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/c5b5331b4a93/cureus-0015-00000035687-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/21faaef01718/cureus-0015-00000035687-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/0698488549cd/cureus-0015-00000035687-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/c5b5331b4a93/cureus-0015-00000035687-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/21faaef01718/cureus-0015-00000035687-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2886/10066709/0698488549cd/cureus-0015-00000035687-i03.jpg

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Ann Noninvasive Electrocardiol. 2013 Sep;18(5):415-20. doi: 10.1111/anec.12082.

本文引用的文献

1
Brugada phenocopies: Current evidence, diagnostic algorithms and a perspective for the future.Brugada综合征拟表型：当前证据、诊断算法及未来展望。
Turk Kardiyol Dern Ars. 2020 Mar;48(2):158-166. doi: 10.5543/tkda.2020.06118.
2
Present Status of Brugada Syndrome: JACC State-of-the-Art Review.Brugada 综合征的现状：美国心脏病学会的最新综述
J Am Coll Cardiol. 2018 Aug 28;72(9):1046-1059. doi: 10.1016/j.jacc.2018.06.037.
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Induced Brugada syndrome: Possible sources of arrhythmogenesis.
Rev Port Cardiol. 2017 Dec;36(12):945-956. doi: 10.1016/j.repc.2017.06.015. Epub 2017 Dec 10.
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Brugada phenocopy in the context of intracranial hemorrhage.颅内出血情况下的Brugada波拟表型
Int J Cardiol. 2014 Dec 20;177(3):e156-7. doi: 10.1016/j.ijcard.2014.08.151. Epub 2014 Aug 30.
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New electrocardiographic criteria to differentiate the Type-2 Brugada pattern from electrocardiogram of healthy athletes with r'-wave in leads V1/V2.用于鉴别2型Brugada波型与V1/V2导联出现r'波的健康运动员心电图的新心电图标准。
Europace. 2014 Nov;16(11):1639-45. doi: 10.1093/europace/euu025. Epub 2014 Mar 6.
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Catastrophic neurologic syndrome with dramatic ECG changes.伴有显著心电图改变的灾难性神经综合征。
J Electrocardiol. 2014 Jan-Feb;47(1):80-3. doi: 10.1016/j.jelectrocard.2013.07.014. Epub 2013 Aug 21.
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Brugada phenocopy: new terminology and proposed classification.Brugada综合征拟表型：新术语及拟分类
Ann Noninvasive Electrocardiol. 2012 Oct;17(4):299-314. doi: 10.1111/j.1542-474X.2012.00525.x. Epub 2012 Aug 13.
8
New electrocardiographic criteria for discriminating between Brugada types 2 and 3 patterns and incomplete right bundle branch block.新的心电图标准可用于鉴别 Brugada 型 2 型和 3 型图形与不完全性右束支传导阻滞。
J Am Coll Cardiol. 2011 Nov 22;58(22):2290-8. doi: 10.1016/j.jacc.2011.08.039.
9
Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report.右束支传导阻滞、持续性ST段抬高与心源性猝死：一种独特的临床和心电图综合征。一项多中心报告。
J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. doi: 10.1016/0735-1097(92)90253-j.