Phang Daniel Sen Kai, Ettikan Jaya Vani, Abd Aziz Hayati, Vendargon Francesca Martina, Sonny Teo Khairy Shamel
Ophthalmology and Visual Sciences, Universiti Sains Malaysia School of Medical Sciences, Kubang Kerian, MYS.
Ophthalmology, Hospital Sultanah Aminah, Johor Bahru, MYS.
Cureus. 2023 Mar 2;15(3):e35693. doi: 10.7759/cureus.35693. eCollection 2023 Mar.
Retrobulbar optic neuritis is a rare complication of herpes zoster ophthalmicus (HZO). We report a case of a 27-year-old man who presented with a progressive left blurring of vision for one week. A history of vesicular rashes in the left trigeminal nerve area preceded his condition. On examination, we noted that his left eye visual acuity was hand movement, and his optic nerve function was reduced. Findings from examining the anterior segment and intraocular pressure were unremarkable. The fundus examination results were normal. A blood investigation was positive for human immunodeficiency virus (HIV). MRI showed hyperintense features of the intraorbital segment of the optic nerve in the T2-weighted image. An abnormal high signal on a T2 weighted image may be present, which may be a clue for varicella zoster associated complications, such as HZO-related optic neuritis. Therefore, a diagnosis of retrobulbar optic neuritis was made, and antiviral treatment was initiated. He received two weeks of IV acyclovir and switched to the oral route for one month. After the completion of the treatment, his visual acuity remained the same.
球后视神经炎是眼部带状疱疹(HZO)的一种罕见并发症。我们报告一例27岁男性患者,其左眼视力渐进性模糊一周。在出现此症状之前,其左侧三叉神经区域有过水疱疹病史。检查时,我们注意到其左眼视力为手动,视神经功能减退。眼前节检查及眼压检查结果无异常。眼底检查结果正常。血液检查显示人类免疫缺陷病毒(HIV)呈阳性。MRI在T2加权图像上显示视神经眶内段呈高信号特征。T2加权图像上可能会出现异常高信号,这可能是水痘带状疱疹相关并发症的线索,如HZO相关性视神经炎。因此,诊断为球后视神经炎,并开始抗病毒治疗。他接受了两周的静脉注射阿昔洛韦治疗,之后转为口服治疗一个月。治疗结束后,他的视力保持不变。