Weisberg L A
J Neurol Neurosurg Psychiatry. 1986 Apr;49(4):346-52. doi: 10.1136/jnnp.49.4.346.
The clinical and computerised tomographic findings in 40 patients with primary pontine haemorrhage were reviewed. Twenty-nine patients were hypertensive. Four patients had angiographic or necropsy evidence of vascular malformations. In 33 cases, there was rapid deterioration to maximal neurological deficit; whereas in seven cases, there was sudden onset but subsequent progression to maximal deficit 24 hours to 5 days following the initial ictus. Seven patients had clinical features considered atypical for pontine haemorrhage. Five patients survived and four of these were capable of performing activities of daily living within 3 months of the haemorrhage. In all cases CT showed a hyperdense non-enhancing brain stem haematoma. There was evidence of ventricular extension in 27 cases. There was CT evidence of subarachnoid blood in only two patients who also had vascular malformations. In 26 cases, there was CT evidence that the haematoma extended to the midbrain and in four cases to the thalamic region. In six cases CT was repeated 6 to 21 days after the initial scan and it showed resolution of the haematoma in size and density; none of the haematomas showed post-contrast enhancement on initial or follow-up CT.
回顾了40例原发性脑桥出血患者的临床及计算机断层扫描结果。29例患者患有高血压。4例患者有血管畸形的血管造影或尸检证据。33例患者迅速恶化至最大神经功能缺损；而7例患者起病突然，但在首次发作后24小时至5天内逐渐发展至最大缺损。7例患者具有被认为是脑桥出血非典型的临床特征。5例患者存活，其中4例在出血后3个月内能够进行日常生活活动。所有病例的CT均显示脑干高密度无强化血肿。27例有脑室扩展证据。仅2例患有血管畸形的患者有蛛网膜下腔出血的CT证据。26例CT显示血肿扩展至中脑，4例扩展至丘脑区域。6例患者在初次扫描后6至21天重复CT检查，结果显示血肿大小和密度有所消退；初次或随访CT检查时，所有血肿均未显示对比剂增强。
