Cook C S, Peiffer R L, Mazzocco T R
J Cataract Refract Surg. 1986 Mar;12(2):130-4. doi: 10.1016/s0886-3350(86)80027-x.
Flexible silicone posterior chamber intraocular lenses made of a proprietary formulation were implanted in rabbits following planned extracapsular lens extraction. The lenses were of three designs: unfenestrated, partially fenestrated, and fully fenestrated haptics. Biostability and tissue reactivity of the silicone lenses and another manufacturer's polymethylmethacrylate lenses appeared equivalent as evaluated clinically by slitlamp biomicroscopy and by light microscopy. The frequency and distribution of lens precipitates were evaluated grossly and by scanning electron microscopy and appeared notably less prominent on the surfaces of the hydrophobic silicone lenses.
在计划进行囊外晶状体摘除术后，将由专有配方制成的柔性硅酮后房型人工晶状体植入兔子体内。这些晶状体有三种设计：无孔、部分有孔和完全有孔的襻。通过裂隙灯生物显微镜和光学显微镜进行临床评估，硅酮晶状体和另一家制造商的聚甲基丙烯酸甲酯晶状体的生物稳定性和组织反应性似乎相当。通过肉眼观察以及扫描电子显微镜对晶状体沉淀物的频率和分布进行评估，结果显示疏水性硅酮晶状体表面的沉淀物明显不那么突出。
