帕金森病患者的自然行走强度。

Natural Walking Intensity in Persons With Parkinson Disease.

机构信息

Departments of Physical Therapy (J.L.G, T.C.B, T.N., F.P., J.A.Z., T.D.E.) and Occupational Therapy (D.F.), Sargent College of Health & Rehabilitation Sciences, Boston University, Boston, Massachusetts; Department of Physical Therapy (J.T.C., M.L.), University of New England, Portland, Maine; Program in Physical Therapy (R.P.D., K.S.R., G.M.E.) and Departments of Neurology (R.P.D., K.S.R., G.M.E.) and Neuroscience (G.M.E.), Washington University School of Medicine in St Louis, St Louis, Missouri; School of Public Health (M.P.L.), Boston University, Boston, Massachusetts; and Department of Neurology (M.S., C.A.T.), Parkinson's Disease and Movement Disorders Center, Boston University, Boston Massachusetts.

出版信息

J Neurol Phys Ther. 2023 Jul 1;47(3):146-154. doi: 10.1097/NPT.0000000000000440. Epub 2023 Apr 4.

DOI:10.1097/NPT.0000000000000440

PMID:37016469

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10330027/

Abstract

BACKGROUND AND PURPOSE

Few persons with Parkinson disease (PD) appear to engage in moderate-intensity walking associated with disease-modifying health benefits. How much time is spent walking at lower, yet still potentially beneficial, intensities is poorly understood. The purpose of this exploratory, observational study was to describe natural walking intensity in ambulatory persons with PD.

METHODS

Accelerometer-derived real-world walking data were collected for more than 7 days at baseline from 82 participants enrolled in a PD clinical trial. Walking intensity was defined according to the number of steps in each active minute (1-19, 20-39, 40-59, 60-79, 80-99, or ≥100 steps). Daily minutes of walking and duration of the longest sustained walking bout were calculated at each intensity. Number of sustained 10 to 19, 20 to 29, and 30-minute bouts and greater at any intensity also were calculated. Values were analyzed in the context of physical activity guidelines.

RESULTS

Most daily walking occurred at lower intensities (157.3 ± 58.1 min of 1-19 steps; 81.3 ± 32.6 min of 20-39 steps; 38.2 ± 21.3 min of 40-59 steps; 15.1 ± 11.5 min of 60-79 steps; 7.4 ± 7.0 min of 80-99 steps; 7.3 ± 9.6 min of ≥100 steps). The longest daily sustained walking bout occurred at the lowest intensity level (15.9 ± 5.2 min of 1-19 steps). Few bouts lasting 20 minutes and greater occurred at any intensity.

DISCUSSION AND CONCLUSIONS

Despite relatively high daily step counts, participants tended to walk at remarkably low intensity, in bouts of generally short duration, with relatively few instances of sustained walking. The findings reinforced the need for health promotion interventions designed specifically to increase walking intensity.Video Abstract available for more insight from authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A426 ).

摘要

背景与目的

很少有帕金森病（PD）患者进行与疾病修饰健康益处相关的中等强度步行。人们对较低但仍具有潜在益处的行走强度下花费了多少时间知之甚少。本探索性观察研究的目的是描述活动状态下 PD 患者的自然行走强度。

方法

从参加 PD 临床试验的 82 名参与者中，在基线时使用加速度计连续采集超过 7 天的真实世界行走数据。根据活跃分钟内的步数（1-19、20-39、40-59、60-79、80-99 或≥100 步）定义行走强度。在每个强度下计算每日行走分钟数和最长持续行走时间。还计算了任何强度下持续 10-19、20-29 和 30 分钟的行走次数和更长时间的行走次数。在体力活动指南的背景下分析了这些数值。

结果

大多数日常行走发生在较低强度下（1-19 步时为 157.3±58.1 分钟；20-39 步时为 81.3±32.6 分钟；40-59 步时为 38.2±21.3 分钟；60-79 步时为 15.1±11.5 分钟；80-99 步时为 7.4±7.0 分钟；≥100 步时为 7.3±9.6 分钟）。最长的每日持续行走时间发生在最低强度水平（1-19 步时为 15.9±5.2 分钟）。任何强度下持续 20 分钟以上的行走次数都很少。