Yu Xianghua, Gong Bin, Yang Hao, Wang Zheng, Qi Gaowei, Sun Jie, Fang Yu, Fan Xiaoli
IEEE Trans Neural Syst Rehabil Eng. 2023;31:729-737. doi: 10.1109/TNSRE.2022.3231899. Epub 2023 Feb 2.
Tinnitus is an auditory phantom percept that affects the perception of sound in the patient's ears, and the incidence of prolonged tinnitus is as high as ten to fifteen percent. Acupuncture is a unique treatment method in Chinese medicine, and it has great advantages in the treatment of tinnitus. However, tinnitus is a subjective symptom of patients, and there is currently no objective detection method to reflect the improvement effect of acupuncture on tinnitus. We used functional near-infrared spectroscopy (fNIRS) to explore the effect of acupuncture on the cerebral cortex of tinnitus patients. We collected the scores of the tinnitus disorder inventory (THI), tinnitus evaluation questionnaire (TEQ), hamilton anxiety scale (HAMA), and hamilton depression scale (HAMD) of eighteen subjects before and after acupuncture treatment, and the fNIRS signals of these subjects in sound-evoked activity before and after acupuncture treatment. According to the fNIRS detection results of tinnitus patients, acupuncture increased the concentration of oxygenated hemoglobin in the temporal lobe of tinnitus patients, and affected the activation of the auditory cortex. The study may reflect the neural mechanisms of acupuncture treatment for tinnitus and ultimately help to provide an objective evaluation method for the therapeutic effect of acupuncture treatment for tinnitus.
耳鸣是一种影响患者耳部声音感知的听觉幻觉，持续性耳鸣的发病率高达10%至15%。针灸是中医独特的治疗方法，在耳鸣治疗方面具有很大优势。然而，耳鸣是患者的主观症状，目前尚无客观检测方法来反映针灸对耳鸣的改善效果。我们采用功能近红外光谱技术（fNIRS）来探究针灸对耳鸣患者大脑皮层的影响。我们收集了18名受试者针灸治疗前后的耳鸣障碍量表（THI）、耳鸣评估问卷（TEQ）、汉密尔顿焦虑量表（HAMA）和汉密尔顿抑郁量表（HAMD）得分，以及这些受试者针灸治疗前后声音诱发活动中的fNIRS信号。根据耳鸣患者的fNIRS检测结果，针灸增加了耳鸣患者颞叶中氧合血红蛋白的浓度，并影响了听觉皮层的激活。该研究可能反映了针灸治疗耳鸣的神经机制，并最终有助于为针灸治疗耳鸣的疗效提供一种客观评估方法。
