Manera Valeria, Fabre Roxane, Daumas Lyne, Zeghari Radia, Derreumaux Alexandre, Payne Magali, Lemaire Justine, Sacco Guillaume, Gros Auriane, Robert Philippe
Université Côte d'Azur, CobTeK, Nice, France.
Association Innovation Alzheimer, Nice, France.
Front Psychiatry. 2023 Mar 20;14:1126479. doi: 10.3389/fpsyt.2023.1126479. eCollection 2023.
Diminished interest is a core feature of apathy that shows high prevalence in people with Mild and Major Neurocognitive disorders (NCD). In the clinical setting, apathy is mainly assessed using clinical scales and questionnaires, but new technologies are starting to be employed to complement classical instruments. Here, we explored the performance of the "Interest game," a ludic application that assesses personal interests, in discriminating between persons with and without diminished interest based on the Apathy Diagnostic Criteria. Two hundred and twenty-seven elderly participants (56 healthy controls, 118 persons with mild-NCD, and 53 with major-NCD) completed the Interest game and were assessed by clinicians concerning the presence and the severity of apathy. Results showed that the application scores varied with the presence of apathy, the type of disorder, and the education level. Cutoff scores calculated for persons with Mild-NCD resulted in a sensitivity of 0.68 and a specificity of 0.65 for the main score index, suggesting the interest of employing this application in the clinical setting to complement the classical assessment.
兴趣减退是冷漠的核心特征，在轻度和重度神经认知障碍（NCD）患者中普遍存在。在临床环境中，冷漠主要通过临床量表和问卷进行评估，但新技术开始被用于补充传统工具。在此，我们基于冷漠诊断标准，探讨了一款评估个人兴趣的游戏化应用程序“兴趣游戏”在区分有无兴趣减退者方面的表现。227名老年参与者（56名健康对照者、118名轻度NCD患者和53名重度NCD患者）完成了“兴趣游戏”，临床医生对他们的冷漠存在情况和严重程度进行了评估。结果显示，应用程序得分随冷漠的存在、疾病类型和教育水平而变化。为轻度NCD患者计算的截断分数，其主要得分指标的敏感性为0.68，特异性为0.65，这表明在临床环境中使用该应用程序以补充传统评估具有一定价值。
