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氧化亚氮+氧气与单纯氧气吸入镇静用于3至12岁儿童下牙槽神经阻滞时焦虑情况的比较评估:一项随机临床试验

Comparative Assessment of Anxiety during Inferior Alveolar Nerve Block under Nitrous Oxide + Oxygen and Oxygen Inhalation Sedation in Children Aged 3-12 Years: A Randomized Clinical Trial.

作者信息

Thomas Princy S, Dave Bhavna H, Shah Devanshi J, John Loyed K

机构信息

Private Practitioner, Jubail, Saudi Arabia.

Department of Pediatric & Preventive Dentistry, K.M. Shah Dental College and Hospital, Vadodara, Gujarat, India.

出版信息

Int J Clin Pediatr Dent. 2023 Jan-Feb;16(1):30-36. doi: 10.5005/jp-journals-10005-2495.

DOI:10.5005/jp-journals-10005-2495
PMID:37020767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10068003/
Abstract

AIM

A comparative evaluation of children's anxiety with the use of nitrous oxide-oxygen (NO-O) inhalation sedation during the administration of inferior alveolar nerve block (IANB).

MATERIALS AND METHODOLOGY

A total of 60 children between 3 and 12 years of age, with Frankl's behavior rating of 2-3 requiring IANB for any dental procedure were enrolled in this randomized clinical study. Group I ( = 30) received NO and oxygen inhalation sedation at a concentration in the range of 25-50%, whereas group II ( = 30) received 100% O as a placebo. The physiological parameters like pulse rate, respiration, blood pressure, and O saturation were measured at the baseline, intraoperatively [during and after administration of local anesthesia (LA)] and postoperatively after the termination of the gases in both groups. The sedation level was measured intraoperatively (before administration of LA) using the Ramsay Sedation Score (RSS). The discomfort and anxiety were measured at the baseline, intraoperatively, and postoperatively using the Face, Legs, Activity, Cry, Consolability (FLACC) behavior scale. The data were evaluated using the statistical software International Business Machines (IBM) Statistical Package for the Social Sciences (SPSS) statistics 20.0.

RESULTS

There was a significant difference in the FLACC scores between the two groups, intraoperatively (-value-0.002), and postoperatively (-value-0.049). The mean of the RSS for group I was 2.80 + 1.03, and for group II was 1.80 + 0.81. All the physiological parameters recorded were within the normal range.

CONCLUSION

The use of NO-O inhalation improved the anxiety levels in children while receiving the IANB and showed significant anxiolytic and sedative effects as compared to O inhalation.

CLINICAL SIGNIFICANCE

Nitrous oxide-oxygen (NO-O) inhalation can be used as a nonpharmacological behavior management adjunct for invasive treatments for children with utmost comfort for the child.

HOW TO CITE THIS ARTICLE

Thomas PS, Dave BH, Shah DJ, Comparative Assessment of Anxiety during Inferior Alveolar Nerve Block under Nitrous Oxide + Oxygen and Oxygen Inhalation Sedation in Children Aged 3-12 Years: A Randomized Clinical Trial. Int J Clin Pediatr Dent 2023;16(1):30-36.

摘要

目的

比较评估在进行下颌牙槽神经阻滞(IANB)时使用氧化亚氮 - 氧气(NO - O)吸入镇静对儿童焦虑的影响。

材料与方法

本随机临床研究纳入了60名3至12岁、Frankl行为评分2 - 3分且因任何牙科手术需要进行IANB的儿童。第一组(n = 30)吸入浓度为25% - 50%的NO和氧气进行镇静,而第二组(n = 30)吸入100%氧气作为安慰剂。在基线、术中(局部麻醉给药期间及之后)和术后两组气体停用后测量心率、呼吸、血压和血氧饱和度等生理参数。术中(局部麻醉给药前)使用Ramsay镇静评分(RSS)测量镇静水平。在基线、术中及术后使用面部、腿部、活动、哭闹、安慰度(FLACC)行为量表测量不适和焦虑程度。使用国际商业机器公司(IBM)社会科学统计软件包(SPSS)统计学20.0对数据进行评估。

结果

两组之间在术中(p值 - 0.002)和术后(p值 - 0.049)的FLACC评分存在显著差异。第一组的RSS平均值为2.80 + 1.03,第二组为1.80 + 0.81。记录的所有生理参数均在正常范围内。

结论

在接受IANB时,使用NO - O吸入可改善儿童的焦虑水平,与吸入氧气相比显示出显著的抗焦虑和镇静作用。

临床意义

氧化亚氮 - 氧气(NO - O)吸入可作为一种非药物行为管理辅助手段,用于对儿童进行侵入性治疗,使儿童获得最大程度的舒适。

如何引用本文

Thomas PS, Dave BH, Shah DJ, 3至12岁儿童在氧化亚氮 + 氧气和氧气吸入镇静下进行下颌牙槽神经阻滞时焦虑的比较评估:一项随机临床试验。《国际临床儿科牙科学杂志》2023;16(1):30 - 36。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/ffa4d604b41b/ijcpd-16-30-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/128e578d8b82/ijcpd-16-30-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/c6ecfad81240/ijcpd-16-30-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/0c4d59a22ef1/ijcpd-16-30-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/f722afc2e2b5/ijcpd-16-30-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/527d329fced9/ijcpd-16-30-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/ffa4d604b41b/ijcpd-16-30-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/128e578d8b82/ijcpd-16-30-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/c6ecfad81240/ijcpd-16-30-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/0c4d59a22ef1/ijcpd-16-30-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/f722afc2e2b5/ijcpd-16-30-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/527d329fced9/ijcpd-16-30-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/797e/10068003/ffa4d604b41b/ijcpd-16-30-g006.jpg

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