Tai Foong Way David, McAlindon Mark, Sidhu Reena
Academic Unit of Gastroenterology, Room P13, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Glossop Road, Sheffield, UK.
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
Curr Gastroenterol Rep. 2023 May;25(5):99-105. doi: 10.1007/s11894-023-00867-8. Epub 2023 Apr 6.
Colon capsule endoscopy (CCE) is a non-invasive, wireless capsule endoscope. In this article, we review its current applications, compare its performance with optical colonoscopy (OC) and alternative imaging modalities like CT colonography (CTC), and highlight developments that may increase potential future use.
By comparison to OC both CCE and CTC have a good sensitivity and specificity in detecting colonic polyps. CCE is more sensitive in detecting sub centimetre polyps. CCE is capable of detecting colonic inflammation and anorectal pathologies, commonly missed by CTC. However, rates of complete CCE examinations are limited by inadequate bowel preparation or incomplete colonic transit, whereas CTC can be performed with less bowel purgatives. Patients tolerate CCE better than OC, however patient preference between CCE and CTC vary. CCE and CTC are both reasonable alternatives to OC. Strategies to improve completion rates and adequacy of bowel preparation will improve cost and clinical effectiveness of CCE.
结肠胶囊内镜检查（CCE）是一种无创的无线胶囊内镜。在本文中，我们回顾其当前应用，将其性能与光学结肠镜检查（OC）以及CT结肠成像（CTC）等替代成像方式进行比较，并强调可能增加其未来潜在用途的进展。
与OC相比，CCE和CTC在检测结肠息肉方面均具有良好的敏感性和特异性。CCE在检测小于1厘米的息肉方面更敏感。CCE能够检测结肠炎症和肛肠病变，而这些病变通常会被CTC漏诊。然而，CCE检查的完整率受到肠道准备不足或结肠转运不完全的限制，而CTC检查所需的肠道泻药较少。患者对CCE的耐受性优于OC，但患者对CCE和CTC的偏好各不相同。CCE和CTC都是OC的合理替代方案。提高完成率和肠道准备充分性的策略将提高CCE的成本效益和临床效果。
