Jung F, Kiesewetter H, Roggenkamp H G, Nüttgens H P, Ringelstein E B, Gerhards M, Kotitschke G, Wenzel E, Zeller H
Klin Wochenschr. 1986 Apr 15;64(8):375-81. doi: 10.1007/BF01728187.
To determine reference ranges for rheologic parameters (hematocrit, plasma viscosity, erythrocyte aggregation, erythrocyte rigidity) a randomized study involving 653 subjects was carried out. Conditions of sampling, transportation and storing of blood specimens were established prior to the survey. Only 283 subjects met the criteria for enrollment in the study; the others were rejected because of inconspicuous history, normal findings in physical and Doppler-sonographic examination and absence of the risk factors hypertension, diabetes mellitus, overweight, rheumatic diseases, and smoking. The reference range for hematocrit was determined by an impedance-measuring device to equal 39-52% for males and 34-50% for females. The reference range for plasma viscosity, measured by a capillary-tube-plasma viscometer, was found to vary from 1.14 mPas to 1.34 mPas. The reference values for the standardized erythrocyte aggregation index was determined with the mini erythrocyte aggregometer to range from 8 to 21. Erythrocytes measured with the selecting-erythrocyte rigidometer showed a rigidity reference range between 0.83 and 1.19. Analysis of the results revealed that the parameters were independent of age (except in young children) and sex (with the exception of hematocrit).
为确定流变学参数（血细胞比容、血浆粘度、红细胞聚集、红细胞刚性）的参考范围，开展了一项涉及653名受试者的随机研究。在调查之前确定了血液标本的采样、运输和储存条件。只有283名受试者符合纳入该研究的标准；其他受试者因病史不明显、体格检查和多普勒超声检查结果正常以及无高血压、糖尿病、超重、风湿性疾病和吸烟等危险因素而被排除。血细胞比容的参考范围通过阻抗测量装置确定，男性为39%至52%，女性为34%至50%。通过毛细管血浆粘度计测量的血浆粘度参考范围为1.14毫帕秒至1.34毫帕秒。使用微型红细胞聚集仪测定的标准化红细胞聚集指数参考值为8至21。用选择式红细胞刚性仪测量的红细胞刚性参考范围在0.83至1.19之间。结果分析表明，这些参数与年龄（幼儿除外）和性别无关（血细胞比容除外）。
