Kumaravel M, Singh M
Biomedical Engineering Division, Indian Institute of Technology, Madras, India.
Indian J Exp Biol. 1995 Jun;33(6):408-15.
The hemorheological parameters, erythrocyte aggregation and deformability are determined in leprotic patients and are compared with that of healthy subjects. The aggregation is determined by sequential analysis of the He-Ne laser transmission data through erythrocyte suspension at hematocrit 5%. The erythrocyte deformability is determined by measurement of passage time (reciprocal of deformability) of erythrocyte suspension in PBS at hematocrit 6% through cellulose membrane. The observations show that in leprosy the aggregation of erythrocyte is marginally reduced and the deformability is significantly increased. These parameters in combination with low hemoglobin and hematocrit levels in these patients lowers the blood viscosity to maintain the transport of material across the capillary wall.
对麻风病患者的血液流变学参数、红细胞聚集性和变形性进行了测定，并与健康受试者进行了比较。聚集性通过对氦氖激光在血细胞比容为5%的红细胞悬液中的透射数据进行连续分析来确定。红细胞变形性通过测量血细胞比容为6%的红细胞悬液在PBS中通过纤维素膜的通过时间（变形性的倒数）来确定。观察结果表明，在麻风病中，红细胞聚集性略有降低，而变形性显著增加。这些参数与这些患者低血红蛋白和血细胞比容水平相结合，降低了血液粘度，以维持物质跨毛细血管壁的运输。
