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部分回肠旁路术对高胆固醇喂养猪回肠形态的影响。

Effect of partial ileal bypass on ileum morphology in cholesterol-fed pigs.

作者信息

Schouten J A, Beynen A C, Meijer S, Hoitsma H F

出版信息

Lab Anim. 1986 Apr;20(2):155-7. doi: 10.1258/002367786780865214.

DOI:10.1258/002367786780865214
PMID:3702324
Abstract

We have studied ileum morphology in pigs 3.5 months after partial ileal bypass (PIB) surgery. PIB caused a reduction in the length of the bypassed ileum by 60%, while the circumference was decreased by about 70%. We did not find evidence for dilatation of the functional, neo-terminal ileum. These results in pigs are contrary to those found earlier in rabbits. This may be of importance concerning the choice of animal model to study the effects of PIB.

摘要

我们研究了部分回肠旁路(PIB)手术后3.5个月猪的回肠形态。PIB使旁路回肠长度减少了60%,而周长减少了约70%。我们没有发现功能性新末端回肠扩张的证据。猪的这些结果与早期在兔子身上发现的结果相反。这对于选择研究PIB效果的动物模型可能具有重要意义。

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Effect of partial ileal bypass on ileum morphology in cholesterol-fed pigs.部分回肠旁路术对高胆固醇喂养猪回肠形态的影响。
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A comparative study on serum lipids and atherosclerotic plaque formation in diet-induced and familial hypercholesterolemia in rabbits, and the effect of partial ileal bypass.饮食诱导和家族性高胆固醇血症兔血清脂质与动脉粥样硬化斑块形成的比较研究及部分回肠旁路的作用
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