Department of Oral Medicine, Dental Research Center, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
Department of Periodontology, Dental Research Center, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
Dent Med Probl. 2023 Jan-Mar;60(1):99-107. doi: 10.17219/dmp/146771.
Sjögren's syndrome (SS) is a common systemic autoimmune disease that affects oral health, and consequently oral health-related quality of life (OHRQoL) due to the involvement of exocrine glands.
The present study aimed to evaluate the oral health-related quality of life and oral health indicators in patients with SS in comparison with healthy individuals.
In the case and control groups (45 patients and 45 healthy individuals), questions about demographic data, other systemic disorders, medications, the years of infection, xerostomia, as well as inquiries about the quality of life (Oral Health Impact Profile-14 - OHIP-14) were asked. The patients were evaluated clinically, and oral health indicators, including the plaque index (PI), the gingival index (GI), the sulcus bleeding index (SBI), and the number of decayed, missing and filled teeth (DMFT) were assessed on the Ramfjord teeth. Unstimulated saliva samples from both groups were obtained and weighed. The data was analyzed using IBM SPSS Statistics for Windows, v. 24.0. Quantitative variables were compared between the case and control groups with the use of the independent t test or their nonparametric equivalent (the Mann-Whitney test).
The comparison of the quantitative variables between the study groups showed a statistically significant difference in the OHRQoL scores (p = 0.037) and the unstimulated saliva flow rate (p = 0.002) between the case and control groups. Also, there was a statistically significant difference in the DMFT index between patients with primary and secondary SS in the case group (p = 0.048).
The lower OHRQoL of patients with SS requires more attention and follow-up to solve periodontal and dental problems in this group of patients.
干燥综合征（SS）是一种常见的系统性自身免疫性疾病，会影响口腔健康，并由于外分泌腺的受累而影响口腔健康相关生活质量（OHRQoL）。
本研究旨在评估 SS 患者的口腔健康相关生活质量和口腔健康指标，并与健康个体进行比较。
在病例组和对照组（45 例患者和 45 例健康个体）中，询问了人口统计学数据、其他系统性疾病、药物、感染年限、口干以及生活质量（口腔健康影响简表-14 版，OHIP-14）等问题。对患者进行了临床评估，并评估了口腔健康指标，包括菌斑指数（PI）、牙龈指数（GI）、龈沟出血指数（SBI）和龋失补牙数（DMFT）。从两组中获得并称重未刺激的唾液样本。使用 IBM SPSS Statistics for Windows，v. 24.0 对数据进行分析。使用独立 t 检验或其非参数等效物（Mann-Whitney 检验）比较病例组和对照组之间的定量变量。
研究组之间定量变量的比较显示，病例组和对照组之间的 OHRQoL 评分（p = 0.037）和未刺激唾液流量（p = 0.002）存在统计学显著差异。此外，病例组原发性和继发性 SS 患者的 DMFT 指数也存在统计学显著差异（p = 0.048）。
SS 患者的 OHRQoL 较低，需要更多关注和随访，以解决该组患者的牙周和牙齿问题。
