同胞兄妹同时发生急性泛发性发疹性脓疱病。
Concurrent acute generalized exanthematous pustulosis in siblings.
机构信息
Department of Dermatology, Venereology and Leprosy, Sardar Patel Medical College, Bikaner, India.
出版信息
Pediatr Dermatol. 2023 Nov-Dec;40(6):1101-1103. doi: 10.1111/pde.15322. Epub 2023 Apr 7.
PMID:37029098
Abstract
Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction triggered in most cases by drugs. It is characterized by abrupt onset and rapid evolution of fields of sterile pustules on an erythematous background. The role of genetic predisposition in this reactive disorder is being explored. We report the simultaneous occurrence of AGEP in two siblings after being exposed to the same drug.
摘要
急性泛发性发疹性脓疱病（AGEP）是一种罕见的严重皮肤不良反应，在大多数情况下由药物引发。其特征为在红斑背景上突然出现并迅速发展的无菌脓疱。遗传易感性在这种反应性疾病中的作用正在被探索。我们报告了两兄弟在接触相同药物后同时发生 AGEP 的情况。
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