Enteric Viruses Group, ICMR-National Institute of Virology, Pune, Maharashtra, India.
Enteric Viruses Group, ICMR-National Institute of Virology, Pune, Maharashtra, India.
Infect Genet Evol. 2023 Jul;111:105432. doi: 10.1016/j.meegid.2023.105432. Epub 2023 Apr 7.
Outbreaks of HFMD in children aged <5 years have been reported worldwide and the major causative agents are Coxsackievirus (CV) A16, enterovirus (EV)-A71 and recently CVA6. In India, HFMD is a disease that is not commonly reported. The purpose of the study was to identify the enterovirus type(s) associated with large outbreak of Hand, foot, and mouth disease during COVID-19 pandemic in 2022. Four hundred and twenty five clinical samples from 196-suspected cases were collected from different parts of the country. This finding indicated the emergence of CVA6 in HFMD along with CVA16, soon after the gradual easing of non-pharmaceutical interventions during-pandemic COVID-19 and the relevance of continued surveillance of circulating enterovirus types in the post-COVID pandemic era.
手足口病在<5 岁儿童中的爆发已在全球范围内得到报告，主要病原体为柯萨奇病毒 A16、肠道病毒（EV）-A71 以及最近的 CVA6。在印度，手足口病并不常见。本研究的目的是确定与 2022 年 COVID-19 大流行期间手足口病大爆发相关的肠道病毒类型。从全国各地的 196 例疑似病例中采集了 425 份临床样本。这一发现表明，在 COVID-19 大流行期间非药物干预逐渐放宽后，CVA6 与 CVA16 一起出现在手足口病中，因此在 COVID 大流行后时代需要继续监测循环肠道病毒类型。
