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评估斑块模型的声学和热学特性。

Evaluating acoustic and thermal properties of a plaque phantom.

机构信息

Electrical Engineering Department, Cyprus University of Technology, 30 Archbishop Kyprianos Street, 3036, Limassol, Cyprus.

出版信息

J Ultrasound. 2024 Sep;27(3):457-470. doi: 10.1007/s40477-023-00778-4. Epub 2023 Apr 8.

Abstract

PURPOSE

The aim of this study is to evaluate the acoustic and thermal properties of a plaque phantom. This is very important for the effective implementation of ultrasound not only in diagnosis but especially in treatment for the future.

MATERIAL AND METHODS

An evaluation of acoustic and thermal properties of plaque phantoms to test their suitability mainly for ultrasound imaging and therapy was presented. The evaluation included measurements of the acoustic propagation speed using pulse-echo technique, ultrasonic attenuation coefficient using through transmission immersion technique, and absorption coefficient. Moreover, thermal properties (thermal conductivity, volumetric specific heat capacity and thermal diffusivity) were measured with the transient method using a needle probe.

RESULTS

It was shown that acoustic and thermal properties of atherosclerotic plaque phantoms fall well within the range of reported values for atherosclerotic plaque and slightly different for thermal diffusivity and volumetric specific heat capacity for soft tissues. The mean value of acoustic and thermal properties and their standard deviation of plaque phantoms were 1523 ± 23 m/s for acoustic speed, 0.50 ± 0.02 W/mK for thermal conductivity, 0.30 ± 0.21 db/cm-MHz for ultrasonic absorption coefficient and 1.63 ± 0.46 db/cm-MHz for ultrasonic attenuation coefficient.

CONCLUSIONS

This study demonstrated that acoustic and thermal properties of atherosclerotic plaque phantoms were within the range of reported values. Future studies should be focused on the optimum recipe of the atherosclerotic plaque phantoms that mimics the human atherosclerotic plaque (agar 4% w/v, gypsum 10% w/v and butter 10% w/v) and can be used for HIFU therapy.

摘要

目的

本研究旨在评估斑块模型的声学和热学特性。这对于超声的有效实施非常重要,不仅在诊断方面,而且在未来的治疗方面都有重要作用。

材料与方法

介绍了一种评估斑块模型声学和热学特性的方法,以测试其主要用于超声成像和治疗的适用性。评估包括使用脉冲回波技术测量声传播速度、使用透射浸没法测量超声衰减系数和吸收系数,并使用针状探头的瞬态法测量热学特性(导热系数、比体积热容和热扩散率)。

结果

结果表明,动脉粥样硬化斑块模型的声学和热学特性在动脉粥样硬化斑块的报告值范围内,与软组织的热扩散率和比体积热容略有不同。斑块模型的平均声学和热学特性及其标准偏差分别为声速 1523 ± 23 m/s、导热系数 0.50 ± 0.02 W/mK、超声吸收系数 0.30 ± 0.21 db/cm-MHz 和超声衰减系数 1.63 ± 0.46 db/cm-MHz。

结论

本研究表明,动脉粥样硬化斑块模型的声学和热学特性在报告值范围内。未来的研究应集中在最佳的动脉粥样硬化斑块模型配方上,以模拟人体动脉粥样硬化斑块(琼脂 4% w/v、石膏 10% w/v 和黄油 10% w/v),并可用于高强度聚焦超声治疗。

相似文献

1
Evaluating acoustic and thermal properties of a plaque phantom.评估斑块模型的声学和热学特性。
J Ultrasound. 2024 Sep;27(3):457-470. doi: 10.1007/s40477-023-00778-4. Epub 2023 Apr 8.

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Development of a high resolution MRI intracranial atherosclerosis imaging phantom.高分辨率 MRI 颅内动脉粥样硬化成像体模的研制。
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