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Burden and trend of colorectal cancer in 54 countries of Africa 2010-2019: a systematic examination for Global Burden of Disease.2010-2019 年非洲 54 个国家的结直肠癌负担和趋势:全球疾病负担的系统评估。
BMC Gastroenterol. 2022 Apr 25;22(1):204. doi: 10.1186/s12876-022-02275-0.
3
Determinants of emergency presentation in patients with colorectal cancer: a systematic review and meta-analysis.结直肠癌患者急诊就诊的决定因素:系统评价和荟萃分析。
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4
Oncological Risk of Colonic Stents Used as Bridge to Surgery for Left-Side Malignant Colonic Obstructions.用于左侧恶性结肠梗阻手术桥梁的结肠支架的肿瘤学风险。
Ann Surg Oncol. 2022 May;29(5):2759-2760. doi: 10.1245/s10434-021-11274-6. Epub 2022 Jan 4.
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与急诊左半结肠手术相关的手术结果和预后因素。

Surgical outcomes and prognostic factors associated with emergency left colonic surgery.

机构信息

From the Department of Surgery, King Abdullah Hospital Bisha, RIyadh, Saudi Arabia.

From the Department of Surgery, Haql General Hospital, Haql, Tabuk, Saudi Arabia.

出版信息

Ann Saudi Med. 2023 Mar-Apr;43(2):97-104. doi: 10.5144/0256-4947.2023.97. Epub 2023 Apr 6.

DOI:10.5144/0256-4947.2023.97
PMID:37031374
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10082940/
Abstract

BACKGROUND

Mortality from emergency left-sided colorectal surgery can be substantial due to acuteness of the presentation and the urgent need to operate in the setting of a limited preparation in a morbid patient.

OBJECTIVES

Determine the 30-day postoperative outcomes and identify risk factors for complications and mortality following emergency colorectal operations.

DESIGN

Retrospective SETTINGS: Three tertiary hospitals in three countries.

PATIENTS AND METHODS

Factors that were studied included age, sex, ASA score, type and extent of the operation, and presence/absence of malignancy. Unadjusted 30-day patient outcomes examined were complications and mortality. Differences in proportions were assessed using the Pearson chi-square test while logistic regression analyses were carried out to evaluate the correlation between risk factors and outcomes.

MAIN OUTCOME MEASURES

30-day postoperative morbidity and mortality SAMPLE SIZE: 104 patients.

RESULTS

Among 104 patients, 70 (67.3%) were men, and 34 (32.7%) were women. The mean (SD) age was 57.2 (17.1) years. The most common indication for emergency colonic surgery was malignant obstruction in 33 (31.7%) patients. The postoperative complication rate was 24% (25/104), and the mortality rate was 12.5% (13/104) within 30 days of the operation. The ASA status (=.02), presence of malignancy (=.02), and the presence of complications (=.004) were significantly related to mortality in the multivariable logistic regression analysis.

CONCLUSIONS

The 30-day mortality of emergency colorectal operations is greatly influenced by the presence of malignancy in the colon and physiological status at the time of the procedure.

LIMITATIONS

The retrospective design and small sample size.

CONFLICT OF INTEREST

None.

摘要

背景

由于发病急骤,且患者身体状况不佳,需要紧急手术,因此,急诊左侧结直肠手术的死亡率可能相当高。

目的

确定急诊结直肠手术后 30 天的术后结果,并确定并发症和死亡率的危险因素。

设计

回顾性

背景

三个国家的三家三级医院。

患者和方法

研究的因素包括年龄、性别、ASA 评分、手术类型和范围,以及是否存在恶性肿瘤。未调整的 30 天患者结果包括并发症和死亡率。使用 Pearson 卡方检验评估比例差异,同时进行逻辑回归分析以评估危险因素与结果之间的相关性。

主要观察指标

30 天术后发病率和死亡率

样本量

104 例患者。

结果

在 104 例患者中,70 例(67.3%)为男性,34 例(32.7%)为女性。平均(SD)年龄为 57.2(17.1)岁。急诊结肠手术最常见的指征是恶性梗阻,共 33 例(31.7%)。术后并发症发生率为 24%(25/104),术后 30 天内死亡率为 12.5%(13/104)。多变量逻辑回归分析显示,ASA 状态(P=0.02)、恶性肿瘤存在(P=0.02)和并发症存在(P=0.004)与死亡率显著相关。

结论

急诊结直肠手术 30 天死亡率受结肠恶性肿瘤和手术时生理状态的显著影响。

局限性

回顾性设计和样本量小。

利益冲突

无。