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用于下肢软组织重建的游离皮瓣——对“银色创伤”患者并发症的系统评价

Free flaps for lower limb soft tissue reconstruction - A systematic review of complications in 'Silver Trauma' patients.

作者信息

Kaur Anjana, Ang Ky-Leigh, Ali Stephen, Dobbs Tom, Pope-Jones Sophie, Harry Lorraine, Whitaker Iain, Emam Ahmed, Marsden Nicholas

机构信息

The Welsh Centre for Burns & Plastic Surgery, Morriston Hospital, Swansea, SA6 6NL, UK.

University of Cardiff, Cardiff CF10 3AT, Wales, United Kingdom.

出版信息

Injury. 2023 Mar 30. doi: 10.1016/j.injury.2023.03.038.

Abstract

BACKGROUND

There are 12.5 million people aged 65 years and older living in the UK. The annual incidence of open fracture is 30.7 per 10,000 person-years. In females, 42.9% of all open fractures occur in patients ≥ 65 years.

METHODS AND MATERIALS

Preferred Reporting for Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed, and the study is registered with PROSPERO (CRD42020209149). The aim was to compare the complication profiles of free fasciocutaneous flaps and free muscular flaps in patients aged over 60 years undergoing lower limb soft tissue reconstruction following an open lower limb fracture. The search strategy based on strict inclusion criteria included PubMed, Embase and Google Scholar.

RESULTS

15 papers were identified, including 46 patients with 10 free fasciocutaneous flaps and 41 free muscle flaps. There were 3 complications in the fasciocutaneous group (30%) and 9 complications in the muscle group (22%). There was a total of 1 secondary procedure in the fasciocutaneous group and 4 in the muscle group.

DISCUSSION

There is insufficient data to provide statistical comparison between free fasciocutaneous versus free muscle flaps for lower limb reconstruction performed in those aged over 60 years. This systematic review highlights evidence for the successful use of free tissue transfer in the older population following an open fracture injury and requiring lower limb reconstruction. There is no evidence to suggest the superiority of one tissue type over the other, with the inference that well vascularised tissue is the most significant factor impacting outcome.

摘要

背景

英国有1250万65岁及以上的老年人。开放性骨折的年发病率为每10000人年30.7例。在女性中,所有开放性骨折的42.9%发生在65岁及以上的患者中。

方法和材料

遵循系统评价和荟萃分析的首选报告项目(PRISMA)指南,该研究已在国际前瞻性系统评价注册库(PROSPERO,注册号:CRD42020209149)登记。目的是比较年龄超过60岁的下肢开放性骨折后进行下肢软组织重建的患者中,游离筋膜皮瓣和游离肌皮瓣的并发症情况。基于严格纳入标准的检索策略包括PubMed、Embase和谷歌学术。

结果

共识别出15篇论文,包括46例患者,其中10例采用游离筋膜皮瓣,41例采用游离肌皮瓣。筋膜皮瓣组有3例并发症(30%),肌皮瓣组有9例并发症(22%)。筋膜皮瓣组共进行了1次二次手术,肌皮瓣组进行了4次。

讨论

对于60岁以上患者进行下肢重建时,游离筋膜皮瓣与游离肌皮瓣之间进行统计学比较的数据不足。本系统评价强调了在开放性骨折损伤后需要进行下肢重建的老年人群中成功使用游离组织移植的证据。没有证据表明一种组织类型优于另一种组织类型,由此推断血运良好的组织是影响结果的最重要因素。

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