Kakobo Patricia K, Kalala Hilaire K, Kelekele Joseph K, Mutombo Paulin B, Nyembue Dieudonné T, Hellings Peter W, Kayembe Jean-Marie N
Department of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Ophthalmology Department, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Front Allergy. 2023 Mar 22;4:1138537. doi: 10.3389/falgy.2023.1138537. eCollection 2023.
To identify the determinants of uncontrolled allergic rhinitis (UCAR) in a hospital setting in Kinshasa, Democratic Republic of Congo.
Hospital-based cross-sectional study of 153 patients with allergic rhinitis (AR). The diagnosis of AR was based on clinical grounds according to the Allergic Rhinitis and its Impact on Asthma (ARIA) criteria. Categorization into controlled AR (CAR) and UCAR was based on the visual analog scale (VAS with cut off point of 5). Binary logistic regression was used to identify factors associated with UCAR.
Patients with UCAR (60.1%) proportionally outnumbered those with CAR (39.9%). There were significantly more patients younger than 30 years of age among patients with UCAR. Factors significantly associated with UCAR were age below 30 years (OR = 3.31; 95% CI: 1.49-7.36; = 0.003), low serum vitamin D level (OR = 3.86; 95% CI: 1.72-8.68; = 0.001), persistent form (OR = 3.11; 95% CI: 1.39-6.98; = 0.006) and moderate to severe form of AR (OR = 4.31; 95% CI: 1.77-10.49; = 0.001).
Factors associated with UCAR in this study population were younger age less than 30 years, low vitamin D level, and persistent as well as moderate to severe AR. Further studies are needed to elucidate the underlying mechanisms favoring the occurrence of these factors.
确定刚果民主共和国金沙萨一家医院中未控制的变应性鼻炎（UCAR）的决定因素。
对153例变应性鼻炎（AR）患者进行基于医院的横断面研究。AR的诊断基于临床依据，按照变应性鼻炎及其对哮喘的影响（ARIA）标准进行。根据视觉模拟量表（VAS，截断点为5）将其分为控制的AR（CAR）和UCAR。采用二元逻辑回归分析确定与UCAR相关的因素。
UCAR患者（60.1%）在比例上多于CAR患者（39.9%）。UCAR患者中30岁以下的患者明显更多。与UCAR显著相关的因素包括年龄低于30岁（OR = 3.31；95%CI：1.49 - 7.36；P = 0.003）、血清维生素D水平低（OR = 3.86；
