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双侧异时性乳腺恶性肿瘤:恶性叶状肿瘤与浸润性乳腺癌——病例报告

Bilateral metachronous breast malignancies: Malignant phylloides and invasive breast carcinoma-a case report.

作者信息

Abdullah Norlia, Rizuana Iqbal Hussain, Goh Janice Hui Ling, Lee Qi Zheng, Md Isa Nurismah, Md Pauzi Suria Hayati

机构信息

Surgery Department, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Malaysia.

Radiology Department, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Malaysia.

出版信息

Front Oncol. 2023 Mar 24;13:1034556. doi: 10.3389/fonc.2023.1034556. eCollection 2023.

Abstract

A 57-year-old Malay nullipara initially presented with a right breast lump that was increasing in size but defaulted follow-up. Two years later, she developed a contralateral breast lump. She only returned to the hospital when the right breast lump had become painful, 4 years from its onset. The biopsy of the right breast lump was a phylloides tumor and that of the left breast lump was a carcinoma. She had bilateral palpable axillary lymph nodes. She underwent bilateral mastectomy and axillary dissection. The pathology report confirmed the right breast lesion to be a malignant phylloides and the left breast lesion to be a carcinoma (pT3N2). She declined adjuvant treatment. A year after the surgical operation of the metachronous lesions, she had a right chest wall recurrence with widespread pulmonary metastases. She was given palliative chemotherapy but succumbed several months later.

摘要

一名57岁未育马来女性最初因右乳肿块就诊,肿块逐渐增大,但她未按要求进行随访。两年后,她对侧乳房出现肿块。自右乳肿块出现4年后,当肿块开始疼痛时,她才再次回到医院。右乳肿块活检为叶状肿瘤,左乳肿块活检为癌。她双侧腋窝可触及肿大淋巴结。她接受了双侧乳房切除术及腋窝淋巴结清扫术。病理报告证实右乳病变为恶性叶状肿瘤,左乳病变为癌(pT3N2)。她拒绝辅助治疗。异时性病变手术一年后,她出现右胸壁复发并伴有广泛肺转移。她接受了姑息化疗,但数月后仍去世。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b6/10080590/d017e7da256b/fonc-13-1034556-g001.jpg

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