输尿管小细胞神经内分泌癌治疗期间PD-1抑制剂引起的心肌梗死：一例报告。

Li Xiaoying, Wen Jing, Li Hongtao, Huang Yan, Zhou Hongliang

Department of Oncology, the People's Hospital of Yubei District of Chongqing City, Chongqing, China.

Front Oncol. 2023 Mar 22;13:1114397. doi: 10.3389/fonc.2023.1114397. eCollection 2023.

Although small cell neuroendocrine carcinoma of the ureter (ureteral SCNEC) is rare, it always leads to a poor prognosis. Also, no treatment recommendation has been given for ureteral SCNEC, with only PD-1/PD-L1 inhibitors being used for its treatment. Here, we report a case of atypical symptoms of cardiac infarction caused by a PD-1 inhibitor used in the treatment of ureteral SCNEC and hope to address concerns regarding the possible cardiac toxicity caused by PD-1/PD-L1 inhibitors in ureteral SCNEC patients.

尽管输尿管小细胞神经内分泌癌（输尿管SCNEC）很罕见，但它总是导致预后不良。此外，对于输尿管SCNEC尚未给出治疗建议，目前仅使用PD-1/PD-L1抑制剂进行治疗。在此，我们报告一例在输尿管SCNEC治疗中使用PD-1抑制剂引起的非典型心肌梗死症状的病例，并希望解决输尿管SCNEC患者中由PD-1/PD-L1抑制剂可能导致的心脏毒性问题。