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接受根治性前列腺切除术治疗的患者在获得机器人技术和围手术期结局方面的差异。

Disparities in access to robotic technology and perioperative outcomes among patients treated with radical prostatectomy.

机构信息

Department of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Surgery Service, Jesse Brown VA Medical Center, Chicago, Illinois, USA.

出版信息

J Surg Oncol. 2023 Aug;128(2):375-384. doi: 10.1002/jso.27274. Epub 2023 Apr 10.

Abstract

BACKGROUND

Most radical prostatectomies are completed with robotic assistance. While studies have previously evaluated perioperative outcomes of robot-assisted radical prostatectomy (RARP), this study investigates disparities in access and clinical outcomes of RARP.

STUDY DESIGN

The National Cancer Database (NCDB) was used to identify patients who received radical prostatectomy for cancer between 2010 and 2017 with outcomes through 2018. RARP was compared to open radical prostatectomy (ORP). Odds of receiving RARP were evaluated while adjusting for covariates. Overall survival was evaluated using a propensity-score matched cohort.

RESULTS

Overall, 354 752 patients were included with 297 676 (83.9%) receiving RARP. Patients who were non-Hispanic Black (82.8%) or Hispanic (81.3%) had lower rates of RARP than non-Hispanic White (84.0%) or Asian patients (87.7%, p < 0.001). Medicaid or uninsured patients were less likely to receive RARP (75.5%) compared to patients with Medicare or private insurance (84.4%, p < 0.001). Medicaid or uninsured status was associated with decreased odds of RARP in adjusted multivariable analysis (OR 0.61, 95% CI 0.49-0.76). RARP was associated with decreased perioperative mortality and improved overall survival compared to ORP.

CONCLUSION

Patients who were underinsured were less likely to receive RARP. Improved access to RARP may lead to decreased disparities in perioperative outcomes for prostate cancer.

摘要

背景

大多数根治性前列腺切除术都采用机器人辅助进行。虽然之前已经有研究评估了机器人辅助根治性前列腺切除术(RARP)的围手术期结果,但本研究调查了 RARP 的可及性和临床结果的差异。

研究设计

本研究使用国家癌症数据库(NCDB),以确定 2010 年至 2017 年间接受前列腺癌根治性切除术且随访至 2018 年的患者。比较了 RARP 与开放根治性前列腺切除术(ORP)。在调整协变量的情况下,评估接受 RARP 的可能性。使用倾向评分匹配队列评估总生存率。

结果

共有 354752 例患者入组,其中 297676 例(83.9%)接受了 RARP。非西班牙裔黑人(82.8%)或西班牙裔(81.3%)患者接受 RARP 的比例低于非西班牙裔白人(84.0%)或亚洲患者(87.7%,p<0.001)。与拥有医疗保险或私人保险的患者相比,医疗补助或无保险患者接受 RARP 的可能性较低(75.5%比 84.4%,p<0.001)。在多变量调整分析中,医疗补助或无保险状态与接受 RARP 的可能性降低相关(OR 0.61,95%CI 0.49-0.76)。与 ORP 相比,RARP 与围手术期死亡率降低和总体生存率提高相关。

结论

未充分投保的患者接受 RARP 的可能性较低。RARP 可及性的提高可能会减少前列腺癌围手术期结果的差异。

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