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新型模块化机器人系统Carina在泌尿外科的初步经验:一项关于安全性、可行性及手术设置的前瞻性研究

Initial experience with the novel modular robotic system Carina in urology: a prospective study on safety feasibility and surgical settings.

作者信息

Pokhrel Gaurab, Wang ZeYuan, Cui Jinshan, Jin Bingzhai, Zheng Haoke, Tao Jin, Fan Yafeng, Liu Yunlong, Zhan Yonghao, Yu Shuanbao, Dong Biao, Zhang Xuepei

机构信息

Department of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.

出版信息

Sci Rep. 2025 Apr 12;15(1):12686. doi: 10.1038/s41598-025-97411-7.

DOI:10.1038/s41598-025-97411-7
PMID:40221629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11993754/
Abstract

Robot-assisted surgery has transformed urology, but widespread adoption remains limited by the high cost, complex setup, and rigid system design. This prospective single-center study evaluates the safety and efficacy of the novel modular Carina in 19 upper and lower urinary tract surgeries. All cases were completed robotically without conversion, with one major complication. For partial nephrectomy (PN), median operative time (OT) was 120 min with 50 mL estimated blood loss (EBL), including one off-clamp PN completed in 77 min (EBL: 50 mL). Pyeloplasty had a median OT of 105 min (EBL: 50 mL), while radical prostatectomy (RP) achieved a median OT of 150 min (EBL: 50 mL). Radical cystectomy was completed in 301 min without major complications, and an uncomplicated postoperative course. Median docking times were 5 and 8 min for upper and lower tract surgeries, with negative margins and preserved renal function in all PN, and social continence post-RP. The Carina system demonstrates procedural safety and feasibility in complex urological procedures. The modular design may enhance workflow and space utilization, suggesting the potential for promising tool and broader clinical applications. Further validation with larger sample sizes and long-term follow-up is needed.

摘要

机器人辅助手术已经改变了泌尿外科,但由于成本高昂、设置复杂以及系统设计僵化,其广泛应用仍然受到限制。这项前瞻性单中心研究评估了新型模块化Carina系统在19例上尿路和下尿路手术中的安全性和有效性。所有病例均通过机器人手术完成,无一例中转,仅发生1例严重并发症。对于部分肾切除术(PN),中位手术时间(OT)为120分钟,估计失血量(EBL)为50毫升,其中1例非阻断性PN手术时间为77分钟(EBL:50毫升)。肾盂成形术的中位OT为105分钟(EBL:50毫升),而根治性前列腺切除术(RP)的中位OT为150分钟(EBL:50毫升)。根治性膀胱切除术在301分钟内完成,无严重并发症,术后恢复顺利。上尿路和下尿路手术的中位对接时间分别为5分钟和8分钟,所有PN手术切缘阴性且肾功能得以保留,RP术后患者达到社会控尿。Carina系统在复杂的泌尿外科手术中显示出操作安全性和可行性。模块化设计可能会提高工作流程和空间利用率,表明其具有开发有前景工具和更广泛临床应用的潜力。需要更大样本量和长期随访进行进一步验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/c4a4a4aeda3c/41598_2025_97411_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/d515e0bf4644/41598_2025_97411_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/e110cc36d1c7/41598_2025_97411_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/c4a4a4aeda3c/41598_2025_97411_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/d515e0bf4644/41598_2025_97411_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/e110cc36d1c7/41598_2025_97411_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7b/11993754/c4a4a4aeda3c/41598_2025_97411_Fig3_HTML.jpg

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Eur Urol Open Sci. 2024 Jul 18;67:7-25. doi: 10.1016/j.euros.2024.06.014. eCollection 2024 Sep.
2
Cost analysis of new robotic competitors: a comparison of direct costs for initial hospital stay between Da Vinci and Hugo RAS for radical prostatectomy.新型机器人竞争者的成本分析:达芬奇与 Hugo RAS 根治性前列腺切除术初始住院费用的直接成本比较。
J Robot Surg. 2024 Jun 13;18(1):251. doi: 10.1007/s11701-024-01930-w.
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A narrative review of the Medtronic Hugo RAS and technical comparison with the Intuitive da Vinci robotic surgical system.对美敦力 Hugo RAS 的叙述性回顾与直观达芬奇机器人手术系统的技术比较。
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