Laboratoire Biophysique et Evolution, CBI, ESPCI Paris, Université PSL, CNRS, Paris, France.
Sorbonne Université, CNRS, Institut de Biologie Paris-Seine (IBPS), Laboratoire Jean Perrin (LJP), Paris.
mSphere. 2023 Jun 22;8(3):e0012323. doi: 10.1128/msphere.00123-23. Epub 2023 Apr 10.
The formation of biofilm at the air-liquid interface of a still flask is related to the emergence of exopolysaccharides (EPS) overproducers. These mutants have the ability to remain near the surface, where oxygen is abundant. Yet, it is still unclear what role oxygen plays in cellular metabolism under this condition. A. Besse, M.-C. Groleau and E. Déziel (mSphere e00057-23, 2023; https://doi.org/10.1128/msphere.00057-23) explains that the redox state of cells is key in understanding the emergence of EPS overproducers. They found that the spatial distribution of oxidizing agent (not oxygen specifically) controls the advantage of remaining near the air-liquid interface, and hence the advantage that EPS-overproduction confers. All together this research paves the way for a deeper comprehension of the relationship between the environment's spatial structure and population dynamics.
在静止瓶中气液界面处形成生物膜与胞外多糖（EPS）过产生菌的出现有关。这些突变体具有靠近富含氧气的表面的能力。然而，在这种条件下，氧气在细胞代谢中扮演什么角色仍不清楚。A. Besse、M.-C. Groleau 和 E. Déziel（mSphere e00057-23，2023；https://doi.org/10.1128/msphere.00057-23）解释说，细胞的氧化还原状态是理解 EPS 过产生菌出现的关键。他们发现，氧化剂（不是特定的氧气）的空间分布控制着靠近气液界面的优势，因此 EPS 过度产生赋予了优势。总的来说，这项研究为深入理解环境的空间结构和种群动态之间的关系铺平了道路。
