尿刊酸可能不是紫外线诱导的接触性超敏反应抑制的光感受器。
Urocanic acid may not be the photoreceptor for UV-induced suppression of contact hypersensitivity.
作者信息
Morison W L, Kelley S P
出版信息
Photodermatol. 1986 Apr;3(2):98-101.
PMID:3703718
Abstract
We have tested the hypothesis that urocanic acid is the photoreceptor molecule for ultraviolet radiation-induced systemic suppression of contact hypersensitivity in the mouse. Almost complete removal of urocanic acid by tape-stripping of exposed skin was not associated with abrogation of immune suppression. This finding makes it unlikely that urocanic acid is the chromophore.
摘要
我们已经对尿刊酸是紫外线辐射诱导小鼠全身接触性超敏反应抑制的光感受器分子这一假说进行了测试。通过对暴露皮肤进行胶带剥离几乎完全去除尿刊酸，这与免疫抑制的消除并无关联。这一发现使得尿刊酸不太可能是发色团。
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