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一个基于Python的用于可视化生物信息学比对算法的教育软件工具。

A Python-based educational software tool for visualizing bioinformatics alignment algorithms.

作者信息

Khatizah Elis, Nam Hee-Jo, Park Hyun-Seok

机构信息

Bioinformatics Laboratory, ELTEC College of Engineering, Ewha Womans University, Seoul 03760, Korea.

Center for Convergence Research of Advanced Technologies, Ewha Womans University, Seoul 03760, Korea.

出版信息

Genomics Inform. 2023 Mar;21(1):e15. doi: 10.5808/gi.22055. Epub 2023 Mar 31.

Abstract

Bioinformatics education can be defined as the teaching and learning of how to use software tools, along with mathematical and statistical analysis, to solve biological problems. Although many resources are available, most students still struggle to understand even the simplest sequence alignment algorithms. Applying visualizations to these topics benefits both lecturers and students. Unfortunately, educational software for visualizing step-bystep processes in the user experience of sequence alignment algorithms is rare. In this article, an educational visualization tool for biological sequence alignment is presented, and the source code is released in order to encourage the collaborative power of open-source software, with the expectation of further contributions from the community in the future. Two different modules are integrated to enable a student to investigate the characteristics of alignment algorithms.

摘要

生物信息学教育可以被定义为关于如何使用软件工具以及数学和统计分析来解决生物学问题的教学。尽管有许多资源可供使用,但大多数学生甚至仍难以理解最简单的序列比对算法。将可视化应用于这些主题对教师和学生都有益。不幸的是,用于在序列比对算法的用户体验中可视化逐步过程的教育软件很少见。在本文中,展示了一种用于生物序列比对的教育可视化工具,并发布了源代码以鼓励开源软件的协作力量,期望未来社区能有更多贡献。集成了两个不同的模块,以使学生能够研究比对算法的特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e3/10085741/54ad0973315b/gi-22055f1.jpg

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