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“手术时机”在无进行性神经功能缺损的腰椎间盘突出症患者治疗中的重要性。

The importance of "time to surgery" in the management of lumbar disc herniation in patients without progressive neurological deficits.

作者信息

Gurung Ishani, Jones Matthew S, Jugurnauth Paul, Wafai Ahmad M

机构信息

Department of Trauma and Orthopaedics, Royal Devon University Healthcare NHS Foundation Trust, Raleigh Heights, Barnstaple, UK.

出版信息

J Spine Surg. 2023 Mar 30;9(1):32-38. doi: 10.21037/jss-22-68. Epub 2023 Feb 7.

Abstract

BACKGROUND

Prolonged sciatica symptoms may result in disability and consequently, absence from work for a longer period. Up to 10% of patients may need surgery but it is difficult to predict and determine which of these patients would improve spontaneously in comparison to those who might benefit from discectomy surgery. We aimed to determine if delay in the "time to surgery" (TTS) has any adverse effects on the patient reported outcome measures (PROMs).

METHODS

Eighty-seven patients after exclusions were selected consecutively. PROMs were comprised of pre-operative, six weeks and six months post-operative back and leg pain visual analogue scores (VAS) and Oswestry disability index (ODI). The differences between these scores were correlated with TTS. Minimal clinically important difference (MCID) of 30% improvement for ODI scores and 33% for VAS scores from baseline were considered as significant improvement. Patients were grouped into TTS less than 6 months and TTS greater than 6 months from referral to TTS. The longest TTS was 18 months. Statistical analysis was done using JASP (Version 0.14.0) [computer software].

RESULTS

The TTS was on average 22.5 weeks. MCID for the leg pain VAS was achieved in 90.2% patients with TTS <6 months and in 80.8% with TTS ≥6 months. The MCID for ODI was achieved in 60.7% with TTS <6 months and in 42.0% with TTS ≥6 months. The MCID for back pain VAS was achieved in 73.8% with TTS <6 months and in 50.0% of patients with TTS ≥6 months. Those who achieved the MCID in ODI score between the two groups were analysed using chi-square test with P=0.115. Those who achieved the MCID in VAS leg pain score between the two groups were analysed using chi-square test with P=0.227. No statistical difference was found in ODI and VAS for leg for patients with TTS before or after 6 months.

CONCLUSIONS

Lumbar discectomies had a positive impact on patient's pain and function in our local district hospital. Delayed surgery of ≥6 months did not cause statistically significant worse outcomes. In the absence of worsening neurological deficit, it may be the wrong approach to define a value for the TTS.

摘要

背景

坐骨神经痛症状持续时间延长可能导致残疾,进而导致更长时间的缺勤。高达10%的患者可能需要手术,但很难预测和确定哪些患者会自发改善,哪些患者可能从椎间盘切除术手术中获益。我们旨在确定“手术时间”(TTS)的延迟是否会对患者报告的结局指标(PROMs)产生任何不利影响。

方法

连续选择87例排除后的患者。PROMs包括术前、术后六周和六个月的背部和腿部疼痛视觉模拟评分(VAS)以及Oswestry功能障碍指数(ODI)。这些评分之间的差异与TTS相关。ODI评分从基线改善30%和VAS评分改善33%的最小临床重要差异(MCID)被视为显著改善。患者从转诊到TTS分为TTS小于6个月和TTS大于6个月两组。最长的TTS为18个月。使用JASP(版本0.14.0)[计算机软件]进行统计分析。

结果

TTS平均为22.5周。TTS<6个月的患者中90.2%达到腿部疼痛VAS的MCID,TTS≥6个月的患者中80.8%达到。TTS<6个月的患者中60.7%达到ODI的MCID,TTS≥6个月的患者中42.0%达到。TTS<6个月的患者中73.8%达到背部疼痛VAS的MCID,TTS≥6个月的患者中50.0%达到。使用卡方检验分析两组中ODI评分达到MCID的患者,P=0.115。使用卡方检验分析两组中腿部疼痛VAS评分达到MCID的患者,P=0.227。TTS在6个月之前或之后的患者在ODI和腿部VAS方面未发现统计学差异。

结论

在我们当地的地区医院,腰椎间盘切除术对患者的疼痛和功能有积极影响。手术延迟≥6个月并未导致统计学上显著更差的结果。在没有神经功能缺损恶化的情况下,为TTS定义一个值可能是错误的做法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db8b/10082427/1a7bc29dbb61/jss-09-01-32-f1.jpg

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