药物、年龄和光照对松鼠猴反应速度的影响。

Effects of drugs, age and illumination on response speed of squirrel monkeys.

作者信息

Steiner N O, Delay E R, Isaac W

出版信息

Pharmacol Biochem Behav. 1986 Mar;24(3):503-6. doi: 10.1016/0091-3057(86)90548-4.

Abstract

Four young (2 1/2 years) and four older (over 10 years) squirrel monkeys were used to study age differences in the effects of d-amphetamine, methylphenidate and illumination on response speed. Although young monkeys were faster than the old monkeys, only the older monkeys showed an illumination effect. Both d-amphetamine and methylphenidate slowed response speed but only in the older monkeys showed an illumination illumination was present. These results suggest that older, mature squirrel monkeys are more sensitive to the effects of d-amphetamine, methylphenidate and illumination than young squirrel monkeys.

摘要

选用了4只年幼（2.5岁）和4只年长（超过10岁）的松鼠猴来研究右旋苯丙胺、哌醋甲酯和光照对反应速度影响的年龄差异。尽管年幼的猴子比年长的猴子反应速度更快，但只有年长的猴子表现出光照效应。右旋苯丙胺和哌醋甲酯均会减慢反应速度，但只有在有光照的情况下年长猴子才会出现这种情况。这些结果表明，年长、成熟的松鼠猴比年幼的松鼠猴对右旋苯丙胺、哌醋甲酯和光照的影响更敏感。