Department of Pulmonary Medicine, Yashoda Hospital, Hyderabad, Telangana, India.
Department of Pathology, Yashoda Hospital, Hyderabad, Telangana, India.
BMJ Case Rep. 2023 Apr 11;16(4):e255317. doi: 10.1136/bcr-2023-255317.
Non-tuberculous mycobacteria (NTM) are ubiquitous organisms. Endobronchial growth as a presenting feature of NTM disease is uncommon. Here we present a case of a patient with retroviral disease on antiretroviral therapy, presenting with cough, wheezing and exertional dyspnoea. High-resolution CT showed a partial obstruction of the left main bronchus (LMB). Bronchoscopy showed an endobronchial growth in the distal LMB. An endobronchial biopsy showed non-necrotising granulomas; bronchial wash for acid-fast bacilli was positive and culture grew complex. He was treated with a combination therapy of clarithromycin, rifampicin and ethambutol. Repeat bronchoscopy after 6 weeks of therapy showed complete resolution of the endobronchial growth.
非结核分枝杆菌(NTM)是无处不在的生物体。作为 NTM 疾病的表现特征,支气管内生长并不常见。在这里,我们报告了一例接受抗逆转录病毒治疗的逆转录病毒疾病患者,其表现为咳嗽、喘息和劳力性呼吸困难。高分辨率 CT 显示左主支气管(LMB)部分阻塞。支气管镜检查显示 LMB 远端有支气管内生长。支气管内膜活检显示非坏死性肉芽肿;支气管冲洗液抗酸杆菌阳性,培养物生长复杂。他接受了克拉霉素、利福平、乙胺丁醇联合治疗。治疗 6 周后复查支气管镜显示支气管内生长完全消退。