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急性原发性闭角型青光眼患眼及其对侧眼即刻进行原发性白内障超声乳化手术的三年随访结果

Three-Year Outcomes of Immediate Primary Phacoemulsification on Acute Primary Angle Closure Eyes and the Fellow Eyes.

作者信息

Suzuki Takafumi, Fujishiro Takashi, Tachi Naoko, Ueta Yoshiki, Okamoto Yasuhiro, Fukutome Takao, Sasajima Hirofumi, Ishida Hidetoshi, Watanabe Yuji, Hashimoto Yoshihiro

机构信息

Department of Ophthalmology, Shinseikai Toyama Hospital, Imizu, Japan.

Department of Ophthalmology, The University of Tokyo Hospital, Bunkyo, Japan.

出版信息

Clin Ophthalmol. 2023 Apr 5;17:1035-1045. doi: 10.2147/OPTH.S406067. eCollection 2023.

Abstract

PURPOSE

This study investigated the long-term outcomes (> 3 years) of immediate primary phacoemulsification in eyes with acute primary angle closure (APAC) and in the fellow eyes with shallow anterior chamber to prevent APAC development.

PATIENTS AND METHODS

This is a retrospective study of phacoemulsification for APAC using bilateral eyes. Best-corrected visual acuity (BCVA), intraocular pressure (IOP), and number of IOP-lowering medications at the preoperative examination (Pre), postoperative month 1 (1m), year 3 (3y), and last visit were compared between 14 eyes with APAC and their 14 fellow eyes. The number of corneal endothelial cells (CECs) at Pre and at more than 2 weeks after phacoemulsification was compared. The visual field mean deviation (MD) within 1 year after phacoemulsification and at the last visit was also compared.

RESULTS

For APAC eyes, BCVA was significantly improved at 1m, 3y, and at the last visit as compared with Pre (p < 0.05). IOP significantly decreased at 1m, 3y, and at the last visit compared with Pre (p < 0.05). IOP-lowering medication use decreased significantly from Pre to 1m (p < 0.05). The number of CECs was not significantly different between Pre and more than 2 weeks after phacoemulsification. BCVA was significantly worse in APAC eyes than in fellow eyes at Pre (p < 0.05). IOP and the number of IOP-lowering medications were significantly higher in APAC eyes than in fellow eyes at Pre (p < 0.05).

CONCLUSION

Primary phacoemulsification improved visual acuity for APAC eyes and maintained good IOP control without the need for reoperation. Moreover, it preserved the number of CECs for the APAC and fellow eyes in the long term.

摘要

目的

本研究调查了急性原发性闭角型青光眼(APAC)患者行即刻原发性超声乳化白内障吸除术的长期预后(>3年),并观察对侧眼前房浅以预防APAC发生的情况。

患者与方法

这是一项使用双眼进行APAC超声乳化白内障吸除术的回顾性研究。比较了14例APAC患者及其14例对侧眼在术前检查(Pre)、术后1个月(1m)、3年(3y)及末次随访时的最佳矫正视力(BCVA)、眼压(IOP)和降眼压药物使用数量。比较了术前及超声乳化白内障吸除术后2周以上的角膜内皮细胞(CEC)数量。还比较了超声乳化白内障吸除术后1年内及末次随访时的视野平均缺损(MD)。

结果

对于APAC眼,与术前相比,1m、3y及末次随访时BCVA显著改善(p<0.05)。与术前相比,1m、3y及末次随访时IOP显著降低(p<0.05)。从术前到1m,降眼压药物使用数量显著减少(p<0.05)。术前与超声乳化白内障吸除术后2周以上的CEC数量无显著差异。术前APAC眼的BCVA显著低于对侧眼(p<0.05)。术前APAC眼的IOP和降眼压药物使用数量显著高于对侧眼(p<0.05)。

结论

原发性超声乳化白内障吸除术改善了APAC眼的视力,维持了良好的眼压控制,无需再次手术。此外,长期来看,它保留了APAC眼及其对侧眼的CEC数量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baed/10083023/c710206e4d8e/OPTH-17-1035-g0001.jpg

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