Shrateh Oadi N, Abugharbieh Yazan, Abbadi Khalid, Maqboul Husni, Hind Ahmad
Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Deparment of Radiology, Al-Ahli Hospital, Hebron, Palestine.
Int J Surg Case Rep. 2023 May;106:108134. doi: 10.1016/j.ijscr.2023.108134. Epub 2023 Apr 7.
Myelolipoma is a rare benign neoplasm composed of mature elements of fatty and hematopoietic tissues. In addition to its low incidence, myelolipoma in kidney transplant patients is much rarer, with only a few cases of this entity reported in the literature.
A 37-year-old diabetic patient was admitted to the hospital due to severe left abdominal pain and elevated creatinine levels of 4.4 mg/dl. The patient has a history of two kidney transplantations. The patient was investigated with different modalities of imaging, which revealed a mass adjacent to the renal graft that was suspicious for malignancy. Histopathological assessment of the resected lesion showed findings consistent with myelolipoma.
Although it's uncommon, myelolipoma should be considered in the differential diagnosis of any renal or extra-renal lesion in kidney transplant patients, including those with a history of graft rejection as in our patient.
In light of the rarity of the lesions, we affirm the significance of the clinicians' reporting such cases that they encounter in order to better understand the disease's biological behavior.
髓脂肪瘤是一种罕见的良性肿瘤，由脂肪组织和造血组织的成熟成分组成。除发病率低外，肾移植患者中的髓脂肪瘤更为罕见，文献中仅报道了少数此类病例。
一名37岁的糖尿病患者因严重的左腹痛和肌酐水平升高至4.4mg/dl入院。该患者有两次肾移植病史。对该患者进行了不同的影像学检查，结果显示肾移植旁有一个肿块，怀疑为恶性。对切除病变的组织病理学评估显示结果与髓脂肪瘤一致。
尽管不常见，但在肾移植患者中，包括像我们的患者有移植排斥史的患者，在对任何肾内或肾外病变进行鉴别诊断时都应考虑髓脂肪瘤。
鉴于这些病变的罕见性，我们肯定临床医生报告他们遇到的此类病例的重要性，以便更好地了解该疾病的生物学行为。
