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隐匿性侵犯:剖析一例肾髓脂肪瘤病例

Stealthy Encroachment: Unraveling an Encounter With Renal Myelolipoma.

作者信息

Sagar Shakti, Hiwale K M, Gadkari Pravin, Naseri Suhit, Khan Simran, Jagtap Miheer M

机构信息

Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Apr 20;16(4):e58628. doi: 10.7759/cureus.58628. eCollection 2024 Apr.

DOI:10.7759/cureus.58628
PMID:38770489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11103626/
Abstract

Myelolipoma of the kidney is an exceedingly unusual benign tumor of hematological components mixed with mature adipose tissue. We present a case of a 59-year-old male who presented with left flank pain and was found to have an atrophic left kidney on imaging studies. A computed tomography (CT) scan revealed a small and shrunken left kidney with an extrarenal pelvis. A diethylenetriamine pentaacetate (DTPA) scan results showed a total glomerular filtration rate (GFR) of 45.6 ml/min with a non-functional left kidney. The patient underwent a left nephrectomy, and a histopathological examination confirmed the diagnosis and highlighted the distinctive morphological features of this rare entity. Postoperatively, the patient experienced a complete resolution of symptoms. This case underscores the importance of considering myelolipoma in the differential diagnosis of renal masses and highlights the successful management of symptomatic cases through surgical intervention. Awareness of this rare tumor is crucial for accurate diagnosis and appropriate management. Further studies are needed to elucidate the natural history and optimal treatment strategies for renal myelolipomas.

摘要

肾髓质脂肪瘤是一种极为罕见的良性肿瘤,由血液学成分与成熟脂肪组织混合而成。我们报告一例59岁男性患者,该患者因左侧胁腹疼痛就诊,影像学检查发现左肾萎缩。计算机断层扫描(CT)显示左肾小且萎缩,伴有肾外肾盂。二乙三胺五乙酸(DTPA)扫描结果显示总肾小球滤过率(GFR)为45.6 ml/分钟,左肾无功能。患者接受了左肾切除术,组织病理学检查确诊并突出了这一罕见实体的独特形态特征。术后,患者症状完全缓解。该病例强调了在肾肿块鉴别诊断中考虑髓质脂肪瘤的重要性,并突出了通过手术干预成功治疗有症状病例的情况。认识这种罕见肿瘤对于准确诊断和适当治疗至关重要。需要进一步研究以阐明肾髓质脂肪瘤的自然病程和最佳治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/f2b0454e60ba/cureus-0016-00000058628-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/1875a529b43a/cureus-0016-00000058628-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/ada92d86d316/cureus-0016-00000058628-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/4c03b8425575/cureus-0016-00000058628-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/e3d76128c766/cureus-0016-00000058628-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/f2b0454e60ba/cureus-0016-00000058628-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/1875a529b43a/cureus-0016-00000058628-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/ada92d86d316/cureus-0016-00000058628-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/4c03b8425575/cureus-0016-00000058628-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/e3d76128c766/cureus-0016-00000058628-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d29/11103626/f2b0454e60ba/cureus-0016-00000058628-i05.jpg

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本文引用的文献

1
A rare case of myelolipoma compressing a second-transplanted kidney: A case report and review of the literature.1例罕见的髓脂肪瘤压迫二次移植肾病例报告并文献复习
Int J Surg Case Rep. 2023 May;106:108134. doi: 10.1016/j.ijscr.2023.108134. Epub 2023 Apr 7.
2
Myelolipoma of renal sinus in a patient with end-stage renal disease: A rare differential diagnosis in renal neoplasms.终末期肾病患者肾窦髓质脂肪瘤:肾肿瘤中一种罕见的鉴别诊断。
SAGE Open Med Case Rep. 2021 Mar 24;9:2050313X211004799. doi: 10.1177/2050313X211004799. eCollection 2021.
3
Renal myelolipoma: a rare extra-adrenal tumor in a rare site: a case report and review of the literature.
肾髓脂肪瘤:一种罕见部位的罕见肾上腺外肿瘤:病例报告及文献复习
J Med Case Rep. 2013 Apr 4;7:92. doi: 10.1186/1752-1947-7-92.
4
Primary myelolipoma presenting as a nasal cavity polyp: a case report and review of the literature.表现为鼻腔息肉的原发性髓脂肪瘤:一例报告并文献复习
J Med Case Rep. 2012 May 14;6:127. doi: 10.1186/1752-1947-6-127.
5
Bilateral extra-adrenal perirenal myelolipomas: CT features.双侧肾上腺外肾周髓脂肪瘤:CT 特征。
Br J Radiol. 2010 Oct;83(994):e198-9. doi: 10.1259/bjr/28801968.
6
Angiomyolipoma with epithelial cysts (AMLEC): a rare but distinct variant of angiomyolipoma.伴上皮样囊肿的血管平滑肌脂肪瘤(AMLEC):一种罕见但独特的血管平滑肌脂肪瘤变体。
Diagn Pathol. 2007 Mar 21;2:11. doi: 10.1186/1746-1596-2-11.
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Retroperitoneal extraadrenal myelolipoma: Technetium-99m sulfur colloid scintigraphy and CT imaging.
Clin Nucl Med. 2007 Feb;32(2):135-8. doi: 10.1097/01.rlu.0000252239.49139.85.
8
Extra-adrenal myelolipoma in the renal hilum: a case report and review of the literature.肾门部肾上腺外髓脂肪瘤:一例报告并文献复习
Arch Pathol Lab Med. 2006 Jul;130(7):1049-52. doi: 10.5858/2006-130-1049-EMITRH.
9
Adrenal myelolipomas show nonrandom X-chromosome inactivation in hematopoietic elements and fat: support for a clonal origin of myelolipomas.肾上腺髓脂肪瘤在造血成分和脂肪中显示出非随机的X染色体失活:支持髓脂肪瘤的克隆起源。
Am J Surg Pathol. 2006 Jul;30(7):838-43. doi: 10.1097/01.pas.0000202044.05333.17.