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基于有效量子探测效率与基于深度学习的肿瘤区域分割精度之间的关系,探讨铜滤器在数字胸部 X 射线摄影中的应用。

Usefulness of copper filters in digital chest radiography based on the relationship between effective detective quantum efficiency and deep learning-based segmentation accuracy of the tumor area.

机构信息

Department of Radiology Division of Medical Technology, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.

Graduate School of Health Sciences, Niigata University, 746 Asahimachidori 2bancho Chuo-ku, Niigata City, Niigata, 951-8518, Japan.

出版信息

Radiol Phys Technol. 2023 Jun;16(2):299-309. doi: 10.1007/s12194-023-00719-0. Epub 2023 Apr 12.

DOI:10.1007/s12194-023-00719-0
PMID:37046154
Abstract

This study aimed to determine the optimal radiographic conditions for detecting lesions on digital chest radiographs using an indirect conversion flat-panel detector with a copper (Cu) filter. First, we calculated the effective detective quantum efficiency (DQE) by considering clinical conditions to evaluate the image quality. We then measured the segmentation accuracy using a U-net convolutional network to verify the effectiveness of the Cu filter. We obtained images of simulated lung tumors using 10-mm acrylic spheres positioned at the right lung apex and left middle lung of an adult chest phantom. The Dice coefficient was calculated as the similarity between the output and learning images to evaluate the accuracy of tumor area segmentation using U-net. Our results showed that effective DQE was higher in the following order up to the spatial frequency of 2 cycles/mm: 120 kV + no Cu, 120 kV + Cu 0.1 mm, and 120 kV + Cu 0.2 mm. The segmented region was similar to the true region for mass-area extraction in the left middle lobe. The lesion segmentation in the upper right lobe with 120 kV + no Cu and 120 kV + Cu 0.1 mm was less successful. However, adding a Cu filter yielded reproducible images with high Dice coefficients, regardless of the tumor location. We confirmed that adding a Cu filter decreases the X-ray absorption efficiency while improving the signal-to-noise ratio (SNR). Furthermore, artificial intelligence accurately segments low-contrast lesions.

摘要

本研究旨在确定使用带有铜(Cu)滤过器的间接转换平板探测器检测数字胸部 X 线摄影中病变的最佳射线照相条件。首先,我们通过考虑临床条件计算了有效探测量子效率(DQE),以评估图像质量。然后,我们使用 U-net 卷积网络测量了分割准确性,以验证 Cu 滤过器的有效性。我们使用位于成人胸部体模右肺尖和左肺中叶的 10mm 丙烯酸球获得了模拟肺肿瘤的图像。使用 Dice 系数作为输出和学习图像之间的相似性来计算 U-net 肿瘤区域分割的准确性。结果表明,有效 DQE 按照以下顺序在 2 周期/mm 的空间频率下更高:120kV+无 Cu、120kV+Cu 0.1mm 和 120kV+Cu 0.2mm。在左肺中叶进行质量面积提取时,分割区域与真实区域相似。120kV+无 Cu 和 120kV+Cu 0.1mm 时右上叶病变的分割效果较差。然而,添加 Cu 滤过器可以产生具有高 Dice 系数的可重复图像,而与肿瘤位置无关。我们证实添加 Cu 滤过器会降低 X 射线吸收效率,同时提高信噪比(SNR)。此外,人工智能可以准确分割低对比度病变。

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Biomedicines. 2022 Nov 7;10(11):2839. doi: 10.3390/biomedicines10112839.
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[Optimal Beam Quality in Chest Radiography Using CsI-flat Panel Detector for Detection of Pulmonary Nodules].[使用碘化铯平板探测器进行胸部X线摄影以检测肺结节时的最佳射束质量]
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