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婆罗门小母牛群体生长和胴体性状的基因组预测准确性

Genomic Prediction Accuracies for Growth and Carcass Traits in a Brangus Heifer Population.

作者信息

Peters Sunday O, Kızılkaya Kadir, Sinecen Mahmut, Mestav Burcu, Thiruvenkadan Aranganoor K, Thomas Milton G

机构信息

Department of Animal Science, Berry College, Mount Berry, GA 30149, USA.

Department of Animal Science, Faculty of Agriculture, Aydin Adnan Menderes University, Aydin 09100, Turkey.

出版信息

Animals (Basel). 2023 Apr 6;13(7):1272. doi: 10.3390/ani13071272.

Abstract

The predictive abilities and accuracies of genomic best linear unbiased prediction (GBLUP) and the Bayesian (BayesA, BayesB, BayesC and Lasso) genomic selection (GS) methods for economically important growth (birth, weaning, and yearling weights) and carcass (depth of rib fat, apercent intramuscular fat and longissimus muscle area) traits were characterized by estimating the linkage disequilibrium (LD) structure in Brangus heifers using single nucleotide polymorphisms (SNP) markers. Sharp declines in LD were observed as distance among SNP markers increased. The application of the GBLUP and the Bayesian methods to obtain the GEBV for growth and carcass traits within k-means and random clusters showed that k-means and random clustering had quite similar heritability estimates, but the Bayesian methods resulted in the lower estimates of heritability between 0.06 and 0.21 for growth and carcass traits compared with those between 0.21 and 0.35 from the GBLUP methodologies. Although the prediction ability of the GBLUP and the Bayesian methods were quite similar for growth and carcass traits, the Bayesian methods overestimated the accuracies of GEBV because of the lower estimates of heritability of growth and carcass traits. However, GBLUP resulted in accuracy of GEBV for growth and carcass traits that parallels previous reports.

摘要

通过使用单核苷酸多态性(SNP)标记估计婆罗门小母牛的连锁不平衡(LD)结构,对基因组最佳线性无偏预测(GBLUP)和贝叶斯(BayesA、BayesB、BayesC和套索)基因组选择(GS)方法对经济上重要的生长(出生、断奶和周岁体重)和胴体(肋脂深度、肌内脂肪百分比和背最长肌面积)性状的预测能力和准确性进行了表征。随着SNP标记之间距离的增加,观察到LD急剧下降。将GBLUP和贝叶斯方法应用于在k均值和随机聚类中获得生长和胴体性状的基因组估计育种值(GEBV)表明,k均值和随机聚类具有相当相似的遗传力估计值,但与GBLUP方法得出的0.21至0.35的遗传力估计值相比,贝叶斯方法得出的生长和胴体性状的遗传力估计值较低,在0.06至0.21之间。尽管GBLUP和贝叶斯方法对生长和胴体性状的预测能力相当相似,但由于生长和胴体性状的遗传力估计值较低,贝叶斯方法高估了GEBV的准确性。然而,GBLUP得出的生长和胴体性状的GEBV准确性与先前的报告相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/486b/10093372/5ebe2bcdca7a/animals-13-01272-g001.jpg

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