So Kyeong A, Shim Seung-Hyuk, Lee Sun Joo, Kim Tae Jin
Department of Obstetrics and Gynecology, KonKuk University Hospital, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.
J Clin Med. 2023 Mar 27;12(7):2518. doi: 10.3390/jcm12072518.
This study aimed to evaluate oncologic characteristics and surgical outcomes in older patients with gynecologic cancers. This retrospective study included patients aged ≥65 years who were diagnosed with gynecologic cancers and underwent surgical treatment between 2005 and 2020. We reviewed the medical records for age at diagnosis, body mass index, American Society of Anesthesiologists score, comorbidities, postoperative complications, cancer stage, histologic type, surgical treatment, postoperative outcome, and survival rate. Data were compared between groups according to the age at the time of diagnosis: <75 years (young-old) and ≥75 years (old-old). In total, 131 patients were identified: 53 (40.5%) with ovarian or primary peritoneal cancer (OC), 44 (33.6%) with endometrial cancer (EC), 30 (22.9%) with cervical cancer, and 4 (3.1%) with leiomyosarcoma. The patients' mean age was 70 (range, 65-83) years; 106 (80.9%) were young-old and 25 (19.1%) were old-old. Postoperative complications occurred in 19 (14.5%) patients. Four patients died within six months after surgery, and three died because of disease progression. There was no difference in the survival rates between the two groups among those with OC and EC. Older patients with gynecologic cancers showed good surgical outcomes and tolerable postoperative complications. Therefore, we can safely offer surgical treatment to older patients.
本研究旨在评估老年妇科癌症患者的肿瘤学特征和手术结果。这项回顾性研究纳入了2005年至2020年间年龄≥65岁、被诊断为妇科癌症并接受手术治疗的患者。我们查阅了病历，记录诊断时的年龄、体重指数、美国麻醉医师协会评分、合并症、术后并发症、癌症分期、组织学类型、手术治疗、术后结果和生存率。根据诊断时的年龄将患者分为两组进行数据比较：<75岁（年轻老年）和≥75岁（高龄老年）。总共确定了131例患者：53例（40.5%）患有卵巢癌或原发性腹膜癌（OC），44例（33.6%）患有子宫内膜癌（EC），30例（22.9%）患有宫颈癌，4例（3.1%）患有平滑肌肉瘤。患者的平均年龄为70岁（范围65 - 83岁）；106例（80.9%）为年轻老年，25例（19.1%）为高龄老年。19例（14.5%）患者发生了术后并发症。4例患者在术后6个月内死亡，3例因疾病进展死亡。OC和EC患者两组之间的生存率没有差异。老年妇科癌症患者显示出良好的手术结果和可耐受的术后并发症。因此，我们可以安全地为老年患者提供手术治疗。
