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心源性休克的早期识别与风险分层:良好的开端是成功的一半。

Early Recognition and Risk Stratification in Cardiogenic Shock: Well Begun Is Half Done.

作者信息

Polyzogopoulou Effie, Bezati Sofia, Karamasis Grigoris, Boultadakis Antonios, Parissis John

机构信息

Emergency Department, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 12462 Athens, Greece.

Second Department of Cardiology, Medical School, Attikon University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece.

出版信息

J Clin Med. 2023 Apr 1;12(7):2643. doi: 10.3390/jcm12072643.

Abstract

Cardiogenic shock is a complex syndrome manifesting with distinct phenotypes depending on the severity of the primary cardiac insult and the underlying status. As long as therapeutic interventions fail to divert its unopposed rapid evolution, poor outcomes will continue challenging health care systems. Thus, early recognition in the emergency setting is a priority, in order to avoid delays in appropriate management and to ensure immediate initial stabilization. Since advanced therapeutic strategies and specialized shock centers may provide beneficial support, it seems that directing patients towards the recently described shock network may improve survival rates. A multidisciplinary approach strategy commands the interconnections between the strategic role of the ED in affiliation with cardiac shock centers. This review outlines critical features of early recognition and initial therapeutic management, as well as the utility of diagnostic tools and risk stratification models regarding the facilitation of patient trajectories through the shock network. Further, it proposes the implementation of precise criteria for shock team activation and the establishment of definite exclusion criteria for streaming the right patient to the right place at the right time.

摘要

心源性休克是一种复杂的综合征,根据原发性心脏损伤的严重程度和基础状态表现出不同的表型。只要治疗干预未能扭转其无法抵抗的快速进展,不良后果将继续给医疗保健系统带来挑战。因此,在急诊环境中早期识别是首要任务,以避免适当管理的延误并确保立即进行初始稳定治疗。由于先进的治疗策略和专业的休克中心可能提供有益的支持,将患者导向最近描述的休克网络似乎可以提高生存率。多学科方法策略掌控着急诊科与心脏休克中心附属关系中的战略作用之间的相互联系。本综述概述了早期识别和初始治疗管理的关键特征,以及诊断工具和风险分层模型在促进患者通过休克网络的治疗过程中的效用。此外,它还提议实施休克团队激活的精确标准,并建立明确的排除标准,以便在正确的时间将合适的患者分流到正确的地方。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd4e/10095596/540d7222ed68/jcm-12-02643-g001.jpg

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