Division of Cardiology, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada.
Can J Cardiol. 2020 Feb;36(2):197-204. doi: 10.1016/j.cjca.2019.11.001. Epub 2019 Nov 9.
Cardiogenic shock (CS) accounts for 15% of all admissions to cardiac intensive care units, with acute myocardial infarction cardiogenic shock (AMICS) accounting for 30% of these. In contrast to other areas in cardiac care in which survival has continued to improve over the last two decades, CS still carries a mortality of around 40%. Temporary mechanical circulatory support (tMCS) therapies have shown inconsistent results in improving outcomes in CS, with the overall evidence not supporting its use, at least in unselected patients. Some of the main stumbling blocks leading to disappointing results of tMCS in CS are challenging patient identification and selection; delayed timing; lack of a systematic approach; inappropriate use of adjunct therapies and tools; lack of escalation/de-escalation and long-term planning; and disparities in regional/centre access to MCS. Among the most promising solutions to this challenge is the cardiogenic shock team (CST), which takes a standardized multidisciplinary approach to the acute management of CS. This paradigm brings expertise from advanced heart failure, interventional cardiology, cardiac surgery, cardiac intensive care, nursing, and others to address all of the aforementioned issues effectively. Unsurprisingly, hurdles to implementation exist, such as establishing effective team dynamics, maintenance of competence, and securing and maintaining adequate resources. However, although the shock-team approach is still in the early stages of clinical evolution, preliminary studies have been encouraging and suggest the value of broader application and evaluation.
心原性休克(CS)占心脏重症监护病房所有入院患者的 15%,其中急性心肌梗死心原性休克(AMICS)占 30%。与过去二十年中在心脏护理的其他领域中生存状况持续改善不同,CS 仍然存在约 40%的死亡率。临时机械循环支持(tMCS)疗法在改善 CS 患者的预后方面并未取得一致的效果,总体证据不支持其应用,至少在未经选择的患者中不支持其应用。导致 tMCS 在 CS 中结果令人失望的一些主要障碍包括:患者识别和选择困难、时机延迟、缺乏系统方法、辅助治疗和工具使用不当、缺乏升级/降级和长期规划以及区域/中心获得 MCS 的差异。为应对这一挑战,最有希望的解决方案之一是心原性休克团队(CST),它采用标准化的多学科方法来急性管理 CS。这种模式汇集了来自先进心力衰竭、介入心脏病学、心脏外科、心脏重症监护、护理和其他领域的专业知识,有效地解决了所有上述问题。毫不奇怪,实施过程中存在障碍,例如建立有效的团队动态、保持能力以及确保和维持足够的资源。然而,尽管休克团队方法仍处于临床发展的早期阶段,但初步研究令人鼓舞,并表明更广泛的应用和评估的价值。