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过去十年间关于刺果番荔枝果实(番荔枝科)生物活性化合物的提取、表征及功能的科学进展

Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit ( Mart.).

作者信息

Arruda Henrique Silvano, Borsoi Felipe Tecchio, Andrade Amanda Cristina, Pastore Glaucia Maria, Marostica Junior Mario Roberto

机构信息

Bioflavors and Bioactive Compounds Laboratory, Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas 13083-862, SP, Brazil.

Nutrition and Metabolism Laboratory, Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas 13083-862, SP, Brazil.

出版信息

Plants (Basel). 2023 Apr 3;12(7):1536. doi: 10.3390/plants12071536.

Abstract

Araticum ( Mart.) is a native and endemic species to Brazilian Cerrado whose fruits have high sensorial, nutritional, bioactive, and economic potential. Its use in local folk medicine, associated with recent scientific findings, has attracted growing interest from different industrial sectors. Therefore, understanding the scientific advances achieved so far and identifying gaps to be filled is essential to direct future studies and transform accumulated knowledge into innovative technologies and products. In this review, we summarize the phytochemical composition, bioactivities, and food products from araticum fruit that have been reported in the scientific literature over the past 10 years. The compiled data showed that araticum fruit parts contain a wide range of bioactive compounds, particularly phenolic compounds, alkaloids, annonaceous acetogenins, carotenoids, phytosterols, and tocols. These phytochemicals contribute to different biological activities verified in araticum fruit extracts/fractions, including antioxidant, anti-inflammatory, anti-Alzheimer, anticancer, antidiabetic, anti-obesity, antidyslipidemic, antinociceptive, hepatoprotective, healing of the cutaneous wound, antibacterial, and insecticide effects. Despite the promising findings, further studies-particularly toxicological (especially, with byproducts), pre-clinical, and clinical trials-must be conducted to confirm these biological effects in humans and assure the safety and well-being of consumers.

摘要

刺果番荔枝(Mart.)是巴西塞拉多地区的本土特有物种,其果实具有很高的感官、营养、生物活性和经济潜力。它在当地民间医学中的应用,以及近期的科学发现,引起了不同工业部门越来越浓厚的兴趣。因此,了解目前已取得的科学进展并找出有待填补的空白,对于指导未来的研究以及将积累的知识转化为创新技术和产品至关重要。在这篇综述中,我们总结了过去10年科学文献中报道的刺果番荔枝果实的植物化学成分、生物活性和食品。汇总的数据表明,刺果番荔枝果实各部分含有多种生物活性化合物,特别是酚类化合物、生物碱、番荔枝内酯、类胡萝卜素、植物甾醇和生育三烯酚。这些植物化学物质促成了在刺果番荔枝果实提取物/馏分中验证的不同生物活性,包括抗氧化、抗炎、抗阿尔茨海默病、抗癌、抗糖尿病、抗肥胖、抗血脂异常、抗伤害感受、保肝、促进皮肤伤口愈合、抗菌和杀虫作用。尽管有这些令人鼓舞的发现,但仍需进一步开展研究——特别是毒理学研究(尤其是对副产品的研究)、临床前研究和临床试验——以证实这些生物效应在人体中的作用,并确保消费者的安全和健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c929/10097317/4232d5ef2981/plants-12-01536-g001.jpg

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