Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Department of Internal Medicine, Division of Cardiology, National Taiwan University Hospital, Taipei, Taiwan.
ESC Heart Fail. 2023 Aug;10(4):2686-2693. doi: 10.1002/ehf2.14374. Epub 2023 Apr 12.
Wet beriberi is a rare but fatal disease in modern society. The nonspecific clinical manifestations, including symptoms of heart failure and recalcitrant lactic acidosis, can prevent timely diagnosis. The use of a pulmonary artery catheter can promptly confirm a high cardiac output state and plays a crucial role in rapidly deteriorating cases. Appropriate treatment with intravenous administration of thiamine leads to dramatic recovery within hours. We present two cases of Shoshin beriberi, a fulminant variant of wet beriberi, diagnosed in 2016 and 2022 at our institute. The patients experienced haemodynamic collapse and refractory lactic acidosis, which were successfully diagnosed with the use of a pulmonary artery catheter and reversed by thiamine supplementation. We also reviewed 19 cases of wet beriberi reported between 2010 and 2022.
湿性脚气病是现代社会罕见但致命的疾病。其非特异性临床表现,包括心力衰竭和难治性乳酸性酸中毒的症状,可能会妨碍及时诊断。肺动脉导管的使用可以迅速确认高心输出量状态,并在病情迅速恶化的情况下发挥关键作用。及时静脉内给予硫胺素治疗可在数小时内显著恢复。我们报告了我院 2016 年和 2022 年诊断的 2 例 Shoshin 脚气病,这是湿性脚气病的暴发性变异。患者出现血流动力学崩溃和难治性乳酸性酸中毒,使用肺动脉导管成功诊断,并通过硫胺素补充逆转。我们还回顾了 2010 年至 2022 年期间报告的 19 例湿性脚气病病例。