Department of Plastic and Reconstructive Surgery, Austin Health, Victoria, Australia.
Surg Technol Int. 2023 Sep 15;42:47-52.
The NovoSorb® Biodegradable Temporising Matrix (BTM) (PolyNovo Biomaterials Pty Ltd, Port Melbourne, Victoria, Australia) is a fully synthetic dermal matrix that can be used to reconstruct complex wounds. It consists of a 2mm-thick NovoSorb® biodegradable polyurethane open-cell foam covered by a non-biodegradable scaling member. Application involves a two-stage procedure. In the first stage, BTM is laid onto a clean wound bed, and in the second stage, the sealing membrane is removed and a split skin graft is applied to the neo-dermis. BTM has been used to reconstruct deep dermal and full-thickness burns, necrotising fasciitis, and free flap donor sites in the early phase. This review documents examples from a comprehensive series of cases in which BTM was applied to a wide range of complex wounds, ranging from hand and fingertip injury, to Dupuytren's surgery, chronic ulcers, post excision of cutaneous malignancies, and hidradenitis suppurativa. BTM can be applied to a wide range of complex wounds which may otherwise require a more challenging reconstruction. It should be considered an important adjunct to the reconstructive ladder.
NovoSorb® 可生物降解临时基质 (BTM)（澳大利亚维多利亚州墨尔本港 PolyNovo Biomaterials Pty Ltd）是一种完全合成的真皮基质，可用于重建复杂伤口。它由 2 毫米厚的 NovoSorb® 可生物降解的聚氨酯开孔泡沫组成，表面覆盖一层不可生物降解的鳞片。应用涉及两阶段程序。在第一阶段，将 BTM 铺在清洁的伤口床上，在第二阶段，去除密封膜并将游离皮片移植到新真皮上。BTM 已用于早期重建深部真皮和全层烧伤、坏死性筋膜炎和游离皮瓣供区。本综述记录了一系列广泛的复杂伤口应用 BTM 的实例，范围从手部和指尖损伤、Dupuytren 手术、慢性溃疡、皮肤恶性肿瘤切除后和化脓性汗腺炎。BTM 可应用于广泛的复杂伤口，否则可能需要更具挑战性的重建。它应被视为重建阶梯的重要辅助手段。
