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NovoSorb® 可生物降解临时基质在复杂创面重建中的应用经验。

Experience with NovoSorb® Biodegradable Temporising Matrix in reconstruction of complex wounds.

机构信息

Department of Plastic and Reconstructive Surgery, Austin Health, Heidelberg, Victoria, Australia.

Department of Plastic and Reconstructive Surgery, Maroondah Hospital, Ringwood East, Victoria, Australia.

出版信息

ANZ J Surg. 2021 Sep;91(9):1744-1750. doi: 10.1111/ans.16936. Epub 2021 Jun 3.

DOI:10.1111/ans.16936
PMID:34085755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8518801/
Abstract

BACKGROUND

The NovoSorb® Biodegradable Temporising Matrix (BTM) is a synthetic polyurethane dermal matrix used to reconstruct complex wounds including deep dermal and full-thickness burns, necrotising fasciitis and free flap donor site. We hope to further explore its potential applications in this series.

METHODS

Patients who received BTM application across four centres over an 18-month period were included. Patients were followed up to assess BTM and graft take, the aesthetic, the return of sensation and complications.

RESULTS

A total of 27 patients with 35 wounds were identified with a range of aetiologies. Thirty-three wounds had 100% integration of BTM at the time of sealing membrane removal. Seven wounds had partial graft loss that later healed by secondary intention. In two cases, re-epithelialisation occurred with BTM alone without split-skin graft.

CONCLUSION

BTM offers a safe and reliable reconstructive option in challenging wounds that would otherwise require more complex operations.

摘要

背景

NovoSorb®可生物降解临时基质(BTM)是一种合成聚氨酯真皮基质,用于重建复杂伤口,包括深真皮和全层烧伤、坏死性筋膜炎和游离皮瓣供区。我们希望在本系列中进一步探索其潜在应用。

方法

纳入在四个中心接受 BTM 应用的患者,为期 18 个月。对患者进行随访以评估 BTM 和移植物的吸收、美观、感觉的恢复和并发症。

结果

共确定了 27 名患者的 35 个伤口,病因各不相同。在封闭膜去除时,有 33 个伤口的 BTM 完全整合。7 个伤口有部分移植物丢失,后来通过二期愈合。在两种情况下,仅用 BTM 即可实现再上皮化,而无需进行皮肤移植。

结论

BTM 为复杂伤口提供了一种安全可靠的重建选择,否则这些伤口需要更复杂的手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/89bcdbe3995f/ANS-91-1744-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/33020cd37fff/ANS-91-1744-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/6b3ded266039/ANS-91-1744-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/89bcdbe3995f/ANS-91-1744-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/33020cd37fff/ANS-91-1744-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/6b3ded266039/ANS-91-1744-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6cc/8518801/89bcdbe3995f/ANS-91-1744-g003.jpg

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