Dana Zelnik Yovel, MD, is Gastroenterologist at Shamir Medical Center, Zerifin, Israel.
Lena Berezovsky, MD, is Pediatrician at Shamir Medical Center, Zerifin, Israel.
Gastroenterol Nurs. 2023;46(3):243-248. doi: 10.1097/SGA.0000000000000729. Epub 2023 Apr 11.
Past studies have reported differences between pediatric and adult celiac disease patients. We aimed to compare factors associated with adherence to a gluten-free diet between these groups. An anonymous online questionnaire was sent via the Israeli Celiac Association and social networks to celiac patients. The Biagi questionnaire was used to assess dietary adherence. A total of 445 subjects participated. Mean age was 25.7 ± 17.5 years and 71.9% were female. Subjects were divided into six groups according to age at diagnosis: younger than 6 years (134 patients, 30.7%), 6-12 (79 patients, 18.1%), 12-18 (41 patients, 9.4%), 18-30 (81 patients, 18.5%), 30-45 (79 patients, 18.1%), and 45 years and above (23 patients, 5.3%). There were several significant differences between childhood- and adulthood-diagnosed patients. Pediatric patients were less likely to be noncompliant with a gluten-free diet (3.7% vs. 9.4%, p < .001). They were also more frequently followed by a gastroenterologist ( p < .001), a dietitian ( p < .001), and participated in a celiac support group ( p = .002). In logistic regression analyses, longer duration of disease was associated with poor compliance. In conclusion, pediatric-diagnosed celiac patients are more adherent to a gluten-free diet than those diagnosed in adulthood, with better social support and nutritional follow-up possibly contributing.
过去的研究报告称，儿科和成人乳糜泻患者之间存在差异。我们旨在比较这两组患者坚持无麸质饮食的相关因素。通过以色列乳糜泻协会和社交网络向乳糜泻患者发送了匿名在线问卷。使用 Biagi 问卷评估饮食依从性。共有 445 名受试者参加。平均年龄为 25.7 ± 17.5 岁，71.9%为女性。根据诊断时的年龄将受试者分为六组：<6 岁（134 例，30.7%）、6-12 岁（79 例，18.1%）、12-18 岁（41 例，9.4%）、18-30 岁（81 例，18.5%）、30-45 岁（79 例，18.1%）和 45 岁及以上（23 例，5.3%）。儿童期和成年期诊断的患者之间存在一些显著差异。儿科患者更不可能不遵守无麸质饮食（3.7%比 9.4%，p<0.001）。他们也更频繁地由胃肠病学家（p<0.001）、营养师（p<0.001）和参加乳糜泻支持小组（p=0.002）随访。在逻辑回归分析中，疾病持续时间较长与不良依从性相关。总之，与成年期诊断的乳糜泻患者相比，儿科诊断的乳糜泻患者更遵守无麸质饮食，这可能与更好的社会支持和营养随访有关。
